Annexin animal models—from fundamental principles to translational research

T Grewal, C Rentero, C Enrich, M Wahba… - International Journal of …, 2021 - mdpi.com
Routine manipulation of the mouse genome has become a landmark in biomedical
research. Traits that are only associated with advanced developmental stages can now be …

Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype

S Hiltbrunner, L Cords, S Kasser, SN Freiberger… - Nature …, 2023 - nature.com
Immune checkpoint inhibitor treatment has the potential to prolong survival in non-small cell
lung cancer (NSCLC), however, some of the patients develop resistance following initial …

Pathobiological functions and clinical implications of annexin dysregulation in human cancers

L Prieto-Fernández, ST Menéndez… - Frontiers in cell and …, 2022 - frontiersin.org
Annexins are an extensive superfamily of structurally related calcium-and phospholipid-
binding proteins, largely conserved and widely distributed among species. Twelve human …

[HTML][HTML] A five-gene expression signature to predict progression in T1G3 bladder cancer

AG van der Heijden, L Mengual, JJ Lozano… - European journal of …, 2016 - Elsevier
Objective The aim of this study was to analyze tumour gene expression profiles of
progressive and non-progressive T1G3 bladder cancer (BC) patients to develop a gene …

Proteome of human stem cells from periodontal ligament and dental pulp

E Eleuterio, O Trubiani, M Sulpizio, F Di Giuseppe… - PLoS …, 2013 - journals.plos.org
Background Many adult tissues contain a population of stem cells with the ability to
regenerate structures similar to the microenvironments from which they are derived in vivo …

Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer

X Wang, Y Zhou, L Ning, J Chen, H Chen, X Li - Cell Death & Disease, 2023 - nature.com
Abstract Annexin A10 (ANXA10) belongs to a family of membrane-bound calcium-
dependent phospholipid-binding proteins, but its precise function remains unclear. Further …

HS3ST2 modulates breast cancer cell invasiveness via MAP kinase‐ and Tcf4 (Tcf7l2)‐dependent regulation of protease and cadherin expression

A Vijaya Kumar, E Salem Gassar… - … journal of cancer, 2014 - Wiley Online Library
Heparan sulfate 3‐O‐sulfotransferase 2 (HS3ST2), an enzyme mediating 3‐O‐sulfation of
heparan sulfate (HS), is silenced by hypermethylation in breast cancer. As HS has an …

Detection of genome-wide copy number variations in two chicken lines divergently selected for abdominal fat content

H Zhang, ZQ Du, JQ Dong, HX Wang, HY Shi, N Wang… - BMC genomics, 2014 - Springer
Abstract Background The chicken (Gallus gallus) is an important model organism that
bridges the evolutionary gap between mammals and other vertebrates. Copy number …

[HTML][HTML] ANXA10 promotes melanoma metastasis by suppressing E3 ligase TRIM41-directed PKD1 degradation

X Zhang, Z Hu, X Wang, L Li, B Zhu, X Lin, J Zhang… - Cancer letters, 2021 - Elsevier
Melanoma is a highly metastatic cancer that requires effective and targeted curative therapy.
Annexin A10 (ANXA10), a member of the annexin family, is a calcium-and phospholipid …

Simvastatin up‐regulates annexin A10 that can inhibit the proliferation, migration, and invasion in androgen‐independent human prostate cancer cells

Y Miyazawa, Y Sekine, H Kato, Y Furuya, H Koike… - The …, 2017 - Wiley Online Library
BACKGROUND Statins have recently been studied for their proapoptotic and antimetastatic
effects. However, the exact mechanisms of their anticancer actions remain unclear. Using …