Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Osteoarthritis (OA) is a complex heterogeneous articular disease with multiple joint tissue
involvement of varying severity and no regulatory-agency-approved disease-modifying …

For the past two decades, the function of intrabony nerves on bone has been a subject of
intense research, while the function of bone on intrabony nerves is still hidden in the corner …

SARS-COV-2 virus is responsible for the ongoing devastating pandemic. Since the early
phase of the pandemic, the “cytokine-storm” appeared a peculiar aspect of SARS-COV-2 …

Osteoarthritis (OA) is a common, debilitating, chronic disease with no disease-modifying
drug approved to date. We discovered LNA043—a derivative of angiopoietin-like 3 …

Osteoarthritis (OA) is a widespread chronic degenerative joint disease characterized by the
degeneration of articular cartilage or inflamed joints. Our findings indicated that treatment …

Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …

Background Use of degradable magnesium (Mg)-based metal implants in orthopaedic
surgeries can avoid drawbacks associated with subsequent removal of the non-degradable …

Stimulator of interferon genes (STING) is activated after detection of cytoplasmic dsDNA by
cGAS (cyclic GMP-AMP synthase) as part of the innate immunity defence against viral …

Strontium (Sr) and strontium ranelate (SR) are commonly used therapeutic drugs for patients
suffering from osteoporosis. Researches have showed that Sr can significantly improve the …