Reporting of observational studies explicitly aiming to emulate randomized trials: a systematic review

HJ Hansford, AG Cashin, MD Jones… - JAMA network …, 2023 - jamanetwork.com
Importance Observational (nonexperimental) studies that aim to emulate a randomized trial
(ie, the target trial) are increasingly informing medical and policy decision-making, but it is …

Designing target trials using electronic health records: A case study of second-line disease-modifying anti-rheumatic drugs and cardiovascular disease outcomes in …

AS Rivera, JB Pierce, A Sinha, AE Pawlowski… - PloS one, 2024 - journals.plos.org
Background Emulation of the “target trial”(TT), a hypothetical pragmatic randomized
controlled trial (RCT), using observational data can be used to mitigate issues commonly …

[HTML][HTML] Focus: Big Data: Comparative Effectiveness Analysis of Lumpectomy and Mastectomy for Elderly Female Breast Cancer Patients: A Deep Learning-based Big …

J Wang, S Zhang, H Yi, S Ma - The Yale Journal of Biology and …, 2023 - ncbi.nlm.nih.gov
Objectives: To evaluate the comparative effectiveness of treatments, a randomized clinical
trial remains the gold standard but can be challenged by a high cost, a limited sample size …

Partial Hepatectomy and Ablation for Survival of Early-Stage Hepatocellular Carcinoma Patients: A Bayesian Emulation Analysis

J Wang, Y Im, R Wang, S Ma - Life, 2024 - mdpi.com
Partial hepatectomy and ablation therapy are two widely used surgical procedures for
localized early-stage hepatocellular carcinoma (HCC) patients. This article aimed to …