Microglia mediated neuroinflammation in Parkinson's disease

S Isik, B Yeman Kiyak, R Akbayir, R Seyhali, T Arpaci - Cells, 2023 - mdpi.com
Parkinson's Disease (PD) is the second most common neurodegenerative disorder seen,
especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance …

Neurodegeneration and neuroinflammation in Parkinson's disease: a self-sustained loop

G Arena, K Sharma, G Agyeah, R Krüger… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …

[HTML][HTML] Anti-IL-6 receptor antibody treatment for severe COVID-19 and the potential implication of IL-6 gene polymorphisms in novel coronavirus pneumonia

ZS Ulhaq, GV Soraya - Medicina Clínica, 2020 - ncbi.nlm.nih.gov
Despite the rapid global increase of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection, there is currently no effective treatment for patients who have …

Microglia and astrocytes dysfunction and key neuroinflammation-based biomarkers in Parkinson's disease

K Chen, H Wang, I Ilyas, A Mahmood, L Hou - Brain Sciences, 2023 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease, with
symptoms such as tremor, bradykinesia with rigidity, and depression appearing in the late …

Quantitative and causal analysis for inflammatory genes and the risk of Parkinson's disease

M Yi, J Li, S Jian, B Li, Z Huang, L Shu… - Frontiers in …, 2023 - frontiersin.org
Background The dysfunction of immune system and inflammation contribute to the
Parkinson's disease (PD) pathogenesis. Cytokines, oxidative stress, neurotoxin and …

Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation

ZS Ulhaq, GB Bittencourt, GV Soraya, LA Istifiani… - Molecular Aspects of …, 2024 - Elsevier
Glaucoma is one of the leading causes of visual impairment and blindness worldwide, and
is characterized by the progressive damage of retinal ganglion cells (RGCs) and the atrophy …

The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis

ZS Ulhaq, GV Soraya, Budu, LR Wulandari - Scientific reports, 2020 - nature.com
Abstract Interleukin-6 (IL-6) is one of the key regulators behind the inflammatory and
pathological process associated with ophthalmic diseases. The role of IL-6-174 G/C …

Inflammation, autoimmunity and neurodegenerative diseases, therapeutics and beyond

JV Garmendia, CV De Sanctis, V Das… - Current …, 2024 - benthamdirect.com
Neurodegenerative disease (ND) incidence has recently increased due to improved life
expectancy. Alzheimer's (AD) or Parkinson's disease (PD) are the most prevalent NDs. Both …

The prevalence of anxiety symptoms and disorders among ophthalmic disease patients

ZS Ulhaq, GV Soraya, NA Dewi… - Therapeutic …, 2022 - journals.sagepub.com
Background: Progressive and irreversible vision loss has been shown to place a patient at
risk of mental health problems such as anxiety. However, the reported prevalence of anxiety …

Vitamin D and its receptor polymorphisms are associated with glaucoma

ZS Ulhaq - Journal Français d'Ophtalmologie, 2020 - Elsevier
Purpose To clarify the association between serum vitamin D levels and its receptor
polymorphisms with glaucoma risk. Methods A meta-analysis was performed from available …