The goal of this review article is to assess how relevant is the concept of dissipative structure
for understanding the dynamical bases of non-equilibrium self-organization in biological …

Genetic and phenotypic heterogeneity contribute to the generation of diverse tumor cell
populations, thus enhancing cancer aggressiveness and therapy resistance. Compared to …

The epithelial–mesenchymal transition (EMT) is a process by which cells lose epithelial
traits, such as cell–cell adhesion and apico-basal polarity, and acquire migratory and …

Regulatory networks as large and complex as those implicated in cell-fate choice are
expected to exhibit intricate, very high-dimensional dynamics. Cell-fate choice, however, is a …

While experimental and theoretical studies have established the prevalence of rhythmic
behaviour at all levels of biological organization, less common is the coexistence between …

The epithelial–mesenchymal transition (EMT) often plays a critical role in cancer metastasis
and chemoresistance, and decoding its dynamics is crucial to design effective therapeutics …

Although the structure of a genetically encoded regulatory circuit is an important determinant
of its function, the relationship between circuit topology and the dynamical behaviors it can …

In the statin era, the incidence of atherosclerotic cardiovascular diseases (ASCVD) in
patients with familial hypercholesterolemia (FH) has not been updated. We aimed to …

Tumor microenvironments contain multiple cell types interacting among one another via
different signaling pathways. Furthermore, both cancer cells and different immune cells can …

Waddington's epigenetic landscape, a famous metaphor in developmental biology, depicts
how a stem cell progresses from an undifferentiated phenotype to a differentiated one. The …