Genetic and epigenetic alterations have been under concentrated investigations for many
years in order to unearth the molecules regulating human cancer pathogenesis. However …

The latest advances in the sequencing methods in head and neck squamous cell carcinoma
(HNSCC) tissues have revolutionized our understanding of the disease by taking off the veil …

The paper describes the synthesis of a new Schiff base As (III) complex followed by the
encapsulation of Schiff base As (III) complex in liposomes. First, As (III) Schiff base complex …

Lung malignancy is one of the prominent causes of cancer death worldwide. However, the
treatment and diagnosis of various lung cancer becoming increasingly challenging …

Acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia characterized
with a translocation between promyelocytic leukemia gene (PML) on chromosome 15 and …

Buparlisib is a highly efficient and selective PI3K inhibitor and a member of the 2, 6‑
dimorpholinopyrimidine‑derived family of compounds. It selectively inhibits four isomers of …

The correlation between the Phosphoinositide 3-kinase (PI3K) axis and crucial mechanisms
involved in the maintenance of the neoplastic nature of multiple myeloma (MM) has recently …

Although conventional therapeutic approaches have brought remarkable advantages for the
treatment of breast cancer (BC), drug-resistance still remains as a leading cause of tumor …

Acute promyelocytic leukemia (APL)/blood cancer is M3 type of acute myeloid leukemia
(AML) formed inside bone marrow through chromosomal translocation mutation usually …

Methods: Public databases were used to search for bioactive compounds in PHEB, their
potential targets, differentially expressed genes associated with APL, and therapeutic targets …