The role of cytochrome P450s in insect toxicology and resistance

R Nauen, C Bass, R Feyereisen… - Annual Review of …, 2022 - annualreviews.org
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

Insecticide resistance and its management in Bemisia tabaci species

AR Horowitz, M Ghanim, E Roditakis, R Nauen… - Journal of Pest …, 2020 - Springer
The sweet potato (cotton) whitefly Bemisia tabaci is a major agricultural pest in various fields
and vegetable crops worldwide. It causes extensive damage by direct feeding on plants …

The global status of insect resistance to neonicotinoid insecticides

C Bass, I Denholm, MS Williamson, R Nauen - Pesticide biochemistry and …, 2015 - Elsevier
The first neonicotinoid insecticide, imidacloprid, was launched in 1991. Today this class of
insecticides comprises at least seven major compounds with a market share of more than …

Transcriptional regulation of xenobiotic detoxification genes in insects-An overview

D Amezian, R Nauen, G Le Goff - Pesticide Biochemistry and Physiology, 2021 - Elsevier
Arthropods have well adapted to the vast array of chemicals they encounter in their
environment. Whether these xenobiotics are plant allelochemicals or anthropogenic …

Neonicotinoids and other insect nicotinic receptor competitive modulators: progress and prospects

JE Casida - Annual Review of Entomology, 2018 - annualreviews.org
Neonicotinoids (neonics) are remarkably effective as plant systemics to control sucking
insects and for flea control on dogs and cats. The nitroimines imidacloprid, clothianidin …

Insect CYP genes and P450 enzymes

R Feyereisen - Insect molecular biology and biochemistry, 2012 - Elsevier
Publisher Summary This chapter discusses the insect CYP genes and P450 enzymes.
Cytochrome P450, or CYP genes, constitutes one of the largest family of genes, with …

Flupyradifurone: a brief profile of a new butenolide insecticide

R Nauen, P Jeschke, R Velten, ME Beck… - Pest management …, 2015 - Wiley Online Library
BACKGROUND The development and commercialisation of new chemical classes of
insecticides for efficient crop protection measures against destructive invertebrate pests is of …

Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods

R Feyereisen, W Dermauw, T Van Leeuwen - Pesticide biochemistry and …, 2015 - Elsevier
The recent accumulation of molecular studies on mutations in insects, ticks and mites
conferring resistance to insecticides, acaricides and biopesticides is reviewed. Resistance is …

[HTML][HTML] Sulfoxaflor and the sulfoximine insecticides: chemistry, mode of action and basis for efficacy on resistant insects

TC Sparks, GB Watson, MR Loso, C Geng… - Pesticide Biochemistry …, 2013 - Elsevier
The sulfoximines, as exemplified by sulfoxaflor ([N-[methyloxido [1-[6-(trifluoromethyl)-3-
pyridinyl] ethyl]-λ 4-sulfanylidene] cyanamide] represent a new class of insecticides …

MAPK-directed activation of the whitefly transcription factor CREB leads to P450-mediated imidacloprid resistance

X Yang, S Deng, X Wei, J Yang… - Proceedings of the …, 2020 - National Acad Sciences
The evolution of insect resistance to pesticides poses a continuing threat to agriculture and
human health. While much is known about the proximate molecular and biochemical …