Purpose This review evaluates the application of bone morphogenetic proteins (BMPs) in
delayed bone repair, aiming at a broad audience from clinicians to scientists. Next to an …

Bone fractures represent a significant medical morbidity among aged population with
osteoporosis. Bone morphogenetic proteins (BMPs) are suggested to have therapeutic …

Abstract Treatment of articular cartilage lesions in the knee remains a challenge for the
practising orthopaedic surgeon. A wide range of options are currently practised, ranging …

We performed a prospective, randomised double-blind study in 24 patients undergoing high
tibial osteotomy to evaluate the effectiveness of human recombinant osteogenic protein (OP …

Barbara A. Ruskin 57 ABSTRACT The present invention provides pharmaceutical composi
tions comprising a morphogenic protein Stimulatory factor (MPSF) for improving the tissue …

Bone morphogenetic proteins (BMPs) are phylogenetically conserved signaling molecules
that belong to the transforming growth factor (TGF)-β superfamily, and are involved in the …

This article presents a strategy for design, engineering, and fabrication of a bioresorbable,
manufactured bone graft substitute (BGS) device. The approach is based on established …

Repair of fractures involves a sequence of dynamic events which ultimately restores the
integrity of the bone and its biomechanical properties. 1 In some cases healing is …

The present invention provides pharmaceutical compositions comprising a morphogenic
protein stimulatory factor (MPSF) for improving the tissue inductive activity of morphogenic …

Purpose The purpose of this study was to revise the clinical use of commercial BMP2
(Infuse) and BMP7 (Osigraft) based bone devices and explore the mechanism of action and …