Serotonin [5-hydroxytryptamine (5-HT)] is a multifunctional neurotransmitter innervating
cortical and limbic areas involved in cognition and emotional regulation. Dysregulation of …

Abstract Serotonin (5-hydroxytryptamien, 5-HT) has been linked to emotional and
motivational aspects of human behavior, including anxiety, depression, impulsivity, etc …

The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

Learning is an essential biological process for survival since it facilitates behavioural
plasticity in response to environmental changes. This process is mediated by a wide variety …

Although serotonin 5-HT1A receptors constitute attractive therapeutic targets, there is a lack
of potential clinical candidates that have a high degree of selectivity and full agonist efficacy …

Drugs acting through 5-hydroxytryptamine (serotonin or 5-HT) systems modulate memory
and its alterations, although the mechanisms involved are poorly understood. 5-HT drugs …

This study utilized pharmacological manipulations to analyze the role of direct and indirect
activation of 5-HT7 receptors (5-HT7Rs) in passive avoidance learning by assessing …

Conditioned fear plays a key role in anxiety disorders as well as depression and other
neuropsychiatric conditions. Understanding how neuromodulators drive the associated …

Agonists and antagonists of the 5-hydroxytryptamine (serotonin) receptor6 (5-HT6) or
receptor7 (5-HT7) might improve memory and/or reverse amnesia, although the …

The basolateral nucleus of the amygdala (BLA) is a key brain region regulating behavioral
changes following stressful events, including social defeat. Previous research has shown …