Synthetic systems powered by biological molecular motors

G Saper, H Hess - Chemical reviews, 2019 - ACS Publications
Biological molecular motors (or biomolecular motors for short) are nature's solution to the
efficient conversion of chemical energy to mechanical movement. In biological systems …

Non-equilibrium assembly of microtubules: from molecules to autonomous chemical robots

H Hess, JL Ross - Chemical Society Reviews, 2017 - pubs.rsc.org
Biological systems have evolved to harness non-equilibrium processes from the molecular
to the macro scale. It is currently a grand challenge of chemistry, materials science, and …

[HTML][HTML] DNA-assisted swarm control in a biomolecular motor system

JJ Keya, R Suzuki, AMR Kabir, D Inoue… - Nature …, 2018 - nature.com
In nature, swarming behavior has evolved repeatedly among motile organisms because it
confers a variety of beneficial emergent properties. These include improved information …

Deep learning: current and emerging applications in medicine and technology

A Akay, H Hess - IEEE journal of biomedical and health …, 2019 - ieeexplore.ieee.org
Machine learning is enabling researchers to analyze and understand increasingly complex
physical and biological phenomena in traditional fields such as biology, medicine, and …

[HTML][HTML] The model of local axon homeostasis-explaining the role and regulation of microtubule bundles in axon maintenance and pathology

I Hahn, A Voelzmann, YT Liew, B Costa-Gomes… - Neural …, 2019 - Springer
Axons are the slender, cable-like, up to meter-long projections of neurons that electrically
wire our brains and bodies. In spite of their challenging morphology, they usually need to be …

[HTML][HTML] Comparison of actin-and microtubule-based motility systems for application in functional nanodevices

C Reuther, R Catalano, A Salhotra… - New Journal of …, 2021 - iopscience.iop.org
Over the last 25 years, extensive progress has been made in developing a range of
nanotechnological applications where cytoskeletal filaments and molecular motors are key …

[HTML][HTML] How neurons maintain their axons long-term: an integrated view of axon biology and pathology

G Smith, ST Sweeney, CJ O'Kane… - Frontiers in Neuroscience, 2023 - frontiersin.org
Axons are processes of neurons, up to a metre long, that form the essential biological cables
wiring nervous systems. They must survive, often far away from their cell bodies and up to a …

Facilitated dynamics of an active polymer in 2D crowded environments with obstacles

S Wu, JX Li, QL Lei - Soft Matter, 2022 - pubs.rsc.org
Understanding the behaviors of a single active chain in complex environments is not only an
interesting topic in non-equilibrium physics but also has applicative implications in …

Engineering with biomolecular motors

H Hess, G Saper - Accounts of chemical research, 2018 - ACS Publications
Conspectus Biomolecular motors, such as the motor protein kinesin, can be used as off-the-
shelf components to power hybrid nanosystems. These hybrid systems combine elements …

Dynamics of active filaments in porous media

Z Mokhtari, A Zippelius - Physical review letters, 2019 - APS
The motion of active polymers in a two-dimensional porous medium is shown to depend
critically on flexibility, activity, and degree of polymerization. For a given Péclet number, we …