[HTML][HTML] New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing
Abstract The Tyrolean Iceman, a 5,300-year-old Copper age individual, was discovered in
1991 on the Tisenjoch Pass in the Italian part of the Ötztal Alps. Here we report the complete …
1991 on the Tisenjoch Pass in the Italian part of the Ötztal Alps. Here we report the complete …
[HTML][HTML] Current status of understanding of the genetic etiology of coronary heart disease
R Pranavchand, BM Reddy - Journal of postgraduate medicine, 2013 - journals.lww.com
Coronary heart disease (CHD), synonymously known as coronary artery disease (CAD) is
the most predominant among the cardiovascular diseases and ranked number one in …
the most predominant among the cardiovascular diseases and ranked number one in …
Association between 9p21 genomic markers and heart disease: a meta-analysis
GE Palomaki, S Melillo, LA Bradley - Jama, 2010 - jamanetwork.com
Context Associations between chromosome 9p21 single-nucleotide polymorphisms (SNPs)
and heart disease have been reported and replicated. If testing improves risk assessments …
and heart disease have been reported and replicated. If testing improves risk assessments …
[HTML][HTML] Genomic correlates of atherosclerosis in ancient humans
Paleogenetics offers a unique opportunity to study human evolution, population dynamics,
and disease evolution in situ. Although histologic and computed x-ray tomographic …
and disease evolution in situ. Although histologic and computed x-ray tomographic …
The chromosome 9p21 risk locus is associated with angiographic severity and progression of coronary artery disease
Aims We tested the hypothesis that the 9p21 risk locus promotes atherosclerosis by
examining the association between rs10757278 and coronary artery disease (CAD) severity …
examining the association between rs10757278 and coronary artery disease (CAD) severity …
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis
Objectives: This study sought to ascertain the relationship of 9p21 locus with: 1)
angiographic coronary artery disease (CAD) burden; and 2) myocardial infarction (MI) in …
angiographic coronary artery disease (CAD) burden; and 2) myocardial infarction (MI) in …
Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus
Background—The presence and severity of coronary artery calcified plaque (CAC) differs
markedly between individuals of African and European descent, suggesting that admixture …
markedly between individuals of African and European descent, suggesting that admixture …
[PDF][PDF] Evaluation of association between common genetic variants on chromosome 9p21 and coronary artery disease in Turkish population
Objective: Coronary artery disease (CAD), which develops from complex interactions
between genetic and enviromental factors, is a leading cause of death worldwide. Based on …
between genetic and enviromental factors, is a leading cause of death worldwide. Based on …
[HTML][HTML] Genome-wide association analysis for severity of coronary artery disease using the gensini scoring system
T Zeller, M Seiffert, C Müller, M Scholz… - Frontiers in …, 2017 - frontiersin.org
Coronary artery disease (CAD) has a complex etiology involving numerous environmental
and genetic factors of disease risk. To date, the genetic 9p21 locus represents the most …
and genetic factors of disease risk. To date, the genetic 9p21 locus represents the most …
[HTML][HTML] The association of 9p21-3 locus with coronary atherosclerosis: a systematic review and meta-analysis
MS Munir, Z Wang, F Alahdab, MW Steffen… - BMC medical …, 2014 - Springer
Background Studies suggest that the 9p21-3 locus may influence susceptibility to
myocardial infarction. We performed a systematic review and meta-analysis to assess …
myocardial infarction. We performed a systematic review and meta-analysis to assess …