Introduction In physiological concentrations, heme is nontoxic to the cell and is essential for
cell survival and proliferation. Increasing intracellular heme concentrations beyond normal …

Solid tumors shed DNA into circulation, and there is growing evidence that the detection of
circulating tumor DNA (ctDNA) has broad clinical utility, including monitoring of disease …

Aim: A confirmed wild-type RAS tumor status is commonly required for prescribing anti-
EGFR treatment for metastatic colorectal cancer. This noninterventional, observational …

Background Circulating tumor DNA (ctDNA) offers a novel and minimally invasive approach
to the detection of the KRAS oncogene mutation in colorectal cancer. This study was …

Background Colvera™ is a test that detects circulating tumor-derived DNA in patients with
colorectal cancer by assaying for the presence of methylated BCAT1 and IKZF1 in blood …

Colorectal cancer (CRC) is a major public health concern and one of the leading causes of
cancer‑related mortality worldwide. The aim of the present study was to determine the serum …

A method and kit for assessing DNA methylation. More particularly, a method of either
qualitatively or quantitatively assessing, with improved sensitivity, the cytosine methylation of …