Heart failure (HF) is a global public health problem with high morbidity and mortality. A large
number of studies have shown that HF is caused by severe energy metabolism disorders …

The pleiotropic hormone relaxin-2 plays a pivotal role in the physiology and pathology of the
cardiovascular system. Relaxin-2 exerts relevant regulatory functions in cardiovascular …

Background The peptide hormone relaxin has potent anti-fibrotic and anti-inflammatory
properties in various organs, including the kidneys. However, the protective effects of relaxin …

Relaxin is a pleiotropic hormone demonstrated to confer cardioprotection in animal models
of myocardial infarction and ischemic heart failure by modulating inflammation, fibrosis and …

Objectives This study was aimed to explore the mechanism of Aconiti Lateralis Radix
Praeparata (ALRP) and Zingiberis Rhizoma (ZR) on doxorubicin (DOX)-induced chronic …

Diabetes mellitus is a metabolic disease with an escalating global prevalence. Despite the
abundance and relative efficacies of current therapeutic approaches, they primarily focus on …

Abstract Recombinant human relaxin-2 (serelaxin) has been widely proven as a novel drug
with myriad effects at different cardiovascular levels, which support its potential therapeutic …

The pregnancy related hormone relaxin is produced throughout the reproductive system.
However, relaxin also has important cardiovascular effects as part of the adaptation that the …

Relaxin is an insulin‐like hormone with pleiotropic protective effects in several organs,
including the liver. We aimed to characterize its role in the control of hepatic metabolism in …

Background This study aimed to evaluate plasma relaxin‑2 (RLN-2) levels in patients with
arterial hypertension (AH) and their relationships with clinical and laboratory parameters …