Objectives/Hypothesis To perform a systematic review of GJB2‐associated hearing loss to
describe genotype distributions and auditory phenotype. Data Sources 230 primary studies …

Objective: The mutation spectrum of the GJB2 and SLC26A4 genes, the 2 most common
genes causing deafness, are known to be ethnic specific. In this study, the spectrum of the …

Hearing loss (HL) is the most prevalent sensory defect affecting 1 in 500 neonates. Genetic
factors are involved in half of the cases. The extreme heterogeneity of HL makes it difficult to …

Our study aimed to investigate GJB2 (connexin 26) and GJB6 (connexin 30) mutations
associated with non-syndromic childhood hearing impairment (HI) as well as the …

Hearing loss (HL) is the most common birth defect and the most prevalent sensorineural
condition worldwide. It is associated with more than 1,000 mutations in at least 90 genes …

Hereditary hearing impairment (HHI) is a common but heterogeneous clinical entity caused
by mutations in a plethora of deafness genes. Research over the past few decades has …

The frequency of inherited bilateral autosomal recessive non-syndromic hearing loss
(ARNSHL) in Pakistan is 1.6/1000 individuals. More than 50% of the families carry mutations …

Objective To determine the prevalence and spectrum of Connexin 26 (GJB2) mutations in
pre-lingual non-syndromic hearing loss (NSHL) patients in authors' centre and to review the …

Genetically caused nonsyndromic hearing loss is highly heterogeneous. Inspite of this large
heterogeneity, mutations in the genes GJB2, GJB6 and SLC26A4 are major contributors …

Hearing loss is the most common communication disorder affecting about 1-7/1000 births
worldwide. The most affected areas are developing countries due toextensively poor health …