Recent Progress in Functionalization of the Pyridine Ring through C− S Bond Formation under Transition Metal Catalyst Free Conditions

OA Tikhanova, DI Bugaenko… - Advanced Synthesis & …, 2024 - Wiley Online Library
Pyridines and quinolines substituted with sulfur‐containing functional groups are widely
used as drugs, drug candidates, organic materials, N, S‐ligands and others. Traditional …

Ts2O Promoted Deoxygenative C–H Dithiocarbonation of Quinoline N-Oxides with Potassium O-Alkyl Xanthates

MY Zhao, JJ Tang, YJ Lin, ZY Tian… - The Journal of Organic …, 2024 - ACS Publications
A simple, efficient, and practical method for the synthesis of S-quinolyl xanthates was
developed via Ts2O-promoted deoxygenative C–H dithiocarbonation of quinoline N-oxides …

Ts 2 O mediated deoxygenative C2-dithiocarbamation of quinoline N-oxides with CS 2 and amines

LY Xie, C Liu, SY Wang, ZY Tian, S Peng - RSC advances, 2024 - pubs.rsc.org
A general, efficient and practical protocol for Ts2O promoted deoxygenative
dithiocarbamation of quinoline N-oxides with in situ generated dithiocarbamic acids from …

TsCl promoted deoxygenative phosphorothiolation of quinoline N-oxides towards S-quinolyl phosphorothioates

LY Wu, T Huang, ZY Tian, XQ Xu, S Peng… - Organic & Biomolecular …, 2024 - pubs.rsc.org
A convenient, efficient and practical approach for the synthesis of S-quinolyl
phosphorothioates via cheap TsCl promoted deoxygenative C2–H phosphorothiolation of …

Site‐Selective Synthetic Modifications of the Cinchona Alkaloids

FP Player, DJ Foley - Asian Journal of Organic Chemistry, 2024 - Wiley Online Library
The natural product quinine has been known to humankind for centuries, and in that time
has played a pivotal role in the treatment of malaria. Quinine, and the related cinchona …

A Palladium-Catalyzed Borylation/Silica Gel Promoted Hydrolysis Sequence for the Synthesis of Hydroquinine-6′-Boric Acid and Its Applications

W Liang, ZJ Chen, LH Ran, L Chen - The Journal of Organic …, 2023 - ACS Publications
Hydroquinine-6′-boric acid was first synthesized via a palladium-catalyzed borylation/silica
gel promoted hydrolysis sequence of hydroquinine-derived triflate and bis (pinacolato) …

Cu(I)-Catalyzed Highly Regioselective C–H Amidation of Quinoline N-Oxides with Dioxazolones

Z Ren, T Feng, T Gao, B Han, R Guo, H Ma… - Organic …, 2024 - ACS Publications
A Cu (I)-catalyzed highly regioselective synthesis of 2-acetamidequinoline N-oxides using
dioxazolones with quinoline N-oxides has been reported. The reaction possesses mild …

BF3-Mediated C2-Amidation of Quinoline N-Oxides Employing Trifluorodiazoethane and Acetonitrile: Access to 2-N-(Trifluoroethyl)amidoquinolines

A Dhami, SP Chandrasekharan, K Mohanan - Organic Letters, 2024 - ACS Publications
A Lewis acid-mediated C2-N-trifluoroethylamidation of quinolines, employing quinoline N-
oxides, trifluorodiazoethane, and acetonitrile to forge a new class of N-(quinolin-2-yl)-N …

Access to 2-thio/selenoquinolines via domino reaction of isocyanides with sulfur and selenium in water

H Liu, M Jia, S Sun, X Xu - Chemical Communications, 2023 - pubs.rsc.org
A domino reaction of o-alkenylaryl isocyanides with elemental sulfur and selenium in pure
water was developed for the efficient and green synthesis of quinoline-2-thione and …

N‐Pyridylureas as Masked Isocyanates Fort the Late‐Stage Diversification of Pyridine‐N‐Oxides

SO Baykova, SV Baykov, KK Geyl, PM Tolstoy… - …, 2024 - Wiley Online Library
A new method for the synthesis of pyridine‐and quinoline‐N‐oxides containing a ureido or
carbamoyl fragment in position 2 has been developed. This method concluded in the …