[HTML][HTML] High-resolution single-cell DNA methylation measurements reveal epigenetically distinct hematopoietic stem cell subpopulations
T Hui, Q Cao, J Wegrzyn-Woltosz, K O'Neill… - Stem cell reports, 2018 - cell.com
Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar
cells examined individually has prompted interest in obtaining parallel methylome data. We …
cells examined individually has prompted interest in obtaining parallel methylome data. We …
Forensic DNA methylation profiling from minimal traces: How low can we go?
J Naue, HCJ Hoefsloot, AD Kloosterman… - Forensic Science …, 2018 - Elsevier
Abstract Analysis of human DNA methylation (DNAm) can provide additional investigative
leads in crime cases, eg the type of tissue or body fluid, the chronological age of an …
leads in crime cases, eg the type of tissue or body fluid, the chronological age of an …
[HTML][HTML] Peripheral mitochondrial DNA, telomere length and DNA methylation as predictors of live birth in in vitro fertilization cycles
L Li Piani, M Reschini, E Somigliana, S Ferrari… - PloS one, 2022 - journals.plos.org
Objective To evaluate whether telomere length (TL), mitochondrial-DNA (mt-DNA) or
epigenetic age estimators based on DNA methylation (DNAm) pattern could be considered …
epigenetic age estimators based on DNA methylation (DNAm) pattern could be considered …
[HTML][HTML] DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia
S Keller, D Punzo, M Cuomo, O Affinito, L Coretti… - Scientific reports, 2018 - nature.com
The spatio-temporal regulation of genes involved in the synthesis and degradation of D-
serine and D-aspartate such as serine racemase (SR), D-amino acid oxidase (DAO), G72 …
serine and D-aspartate such as serine racemase (SR), D-amino acid oxidase (DAO), G72 …
Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene
E Florio, S Keller, L Coretti, O Affinito, G Scala… - Epigenetics, 2017 - Taylor & Francis
We performed ultra-deep methylation analysis at single molecule level of the promoter
region of developmentally regulated D-Aspartate oxidase (Ddo), as a model gene, during …
region of developmentally regulated D-Aspartate oxidase (Ddo), as a model gene, during …
[HTML][HTML] Modeling DNA methylation profiles through a dynamic equilibrium between methylation and demethylation
G De Riso, DFG Fiorillo, A Fierro, M Cuomo, L Chiariotti… - Biomolecules, 2020 - mdpi.com
DNA methylation is a heritable epigenetic mark that plays a key role in regulating gene
expression. Mathematical modeling has been extensively applied to unravel the regulatory …
expression. Mathematical modeling has been extensively applied to unravel the regulatory …
[HTML][HTML] Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize
M Lauria, RA Echegoyen-Nava, D Rodríguez-Ríos… - BMC Plant …, 2017 - Springer
Background Variation in DNA methylation across distinct genetic populations, or in response
to specific biotic or abiotic stimuli, has typically been studied in leaf DNA from pooled …
to specific biotic or abiotic stimuli, has typically been studied in leaf DNA from pooled …
[HTML][HTML] Leveraging locus-specific epigenetic heterogeneity to improve the performance of blood-based DNA methylation biomarkers
BF Miller, TR Pisanic II, G Margolin, HM Petrykowska… - Clinical …, 2020 - Springer
Background Variation in intercellular methylation patterns can complicate the use of
methylation biomarkers for clinical diagnostic applications such as blood-based cancer …
methylation biomarkers for clinical diagnostic applications such as blood-based cancer …
Modeling methylation patterns with long read sequencing data
KN Meyer, MR Lacey - IEEE/ACM Transactions on …, 2017 - ieeexplore.ieee.org
Variation in cytosine methylation at CpG dinucleotides is often observed in genomic regions,
and analysis typically focuses on estimating the proportion of methylated sites observed in a …
and analysis typically focuses on estimating the proportion of methylated sites observed in a …
Brain Area-Specific Methylation Signatures Mark Patients With Schizophrenia
V Morgera, A Feola, T Improda, M Cuomo, A Porcellini… - 2023 - preprints.org
Abstract D-Aspartate and D-Serine serve as primary agonists at glutamate receptors, playing
a crucial role in modulating synaptic plasticity and cell migration within the central nervous …
a crucial role in modulating synaptic plasticity and cell migration within the central nervous …