Integrins are heterodimeric transmembrane cell adhesion molecules made up of alpha (α)
and beta (β) subunits arranged in numerous dimeric pairings. These complexes have …

Platelets have long been recognized as key players in hemostasis and thrombosis;
however, growing evidence suggests that they are also significantly involved in cancer, the …

Background Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic
state that places them at a dramatically increased lethal risk. Although platelet activation is …

Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

Immune thrombocytopenia (ITP) is a common bleeding disorder caused primarily by
autoantibodies against platelet GPIIbIIIa and/or the GPIb complex. Current theory suggests …

Platelets are small anucleate cells generated from megakaryocytes in the bone marrow.
Although platelet generation, maturation, and clearance are still not fully understood …

Although platelets are best known as primary mediators of hemostasis, this function
intimately associates them with inflammatory processes, and it has been increasingly …

Platelets, small anucleate cells circulating in the blood, are critical mediators in haemostasis
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …

Platelets are central mediators of thrombosis and hemostasis. At the site of vascular injury,
platelet accumulation (ie adhesion and aggregation) constitutes the first wave of hemostasis …

Plasma fibronectin (pFn) has long been suspected to be involved in hemostasis; however,
direct evidence has been lacking. Here, we demonstrated that pFn is vital to control bleeding …