Gut microbiome lipid metabolism and its impact on host physiology
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …
recognition by the immune system and their influence on numerous metabolic pathways …
Pathogenicity and virulence of Clostridium perfringens
I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …
[HTML][HTML] Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial
Background & Aims Rifaximin-α is efficacious for the prevention of recurrent hepatic
encephalopathy (HE), but its mechanism of action remains unclear. We postulated that …
encephalopathy (HE), but its mechanism of action remains unclear. We postulated that …
Bacteriophage-encoded depolymerases: their diversity and biotechnological applications
Bacteriophages (phages), natural enemies of bacteria, can encode enzymes able to
degrade polymeric substances. These substances can be found in the bacterial cell surface …
degrade polymeric substances. These substances can be found in the bacterial cell surface …
Emerging principles for the therapeutic exploitation of glycosylation
Background Glycoproteins and glycolipids exist as an ensemble of glycosylated variants, or
glycoforms. Specific glycoforms are directly modulated by microenvironmental cues and play …
glycoforms. Specific glycoforms are directly modulated by microenvironmental cues and play …
Utilisation of Mucin Glycans by the Human Gut Symbiont Ruminococcus gnavus Is Strain-Dependent
EH Crost, LE Tailford, G Le Gall, M Fons, B Henrissat… - PloS one, 2013 - journals.plos.org
Commensal bacteria often have an especially rich source of glycan-degrading enzymes
which allow them to utilize undigested carbohydrates from the food or the host. The species …
which allow them to utilize undigested carbohydrates from the food or the host. The species …
Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source
SJ Siegel, AM Roche, JN Weiser - Cell host & microbe, 2014 - cell.com
Much of the mortality attributed to influenza virus is due to secondary bacterial pneumonia,
particularly from Streptococcus pneumoniae. However, mechanisms underlying this …
particularly from Streptococcus pneumoniae. However, mechanisms underlying this …
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut
Sialic acid (N-acetylneuraminic acid (Neu5Ac)) is commonly found in the terminal location of
colonic mucin glycans where it is a much-coveted nutrient for gut bacteria, including …
colonic mucin glycans where it is a much-coveted nutrient for gut bacteria, including …
The Structure of the Human Vaginal Stratum Corneum and its Role in Immune Defense
DJ Anderson, J Marathe… - American journal of …, 2014 - Wiley Online Library
The superficial layers of the human vaginal epithelium, which form an interface between
host and environment, are comprised of dead flattened cells that have undergone a terminal …
host and environment, are comprised of dead flattened cells that have undergone a terminal …
Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation
The gastrointestinal mucus layer is colonized by a dense community of microbes
catabolizing dietary and host carbohydrates during their expansion in the gut. Alterations in …
catabolizing dietary and host carbohydrates during their expansion in the gut. Alterations in …