Epileptogenesis is defined as the process of developing epilepsy—a disorder characterized
by recurrent seizures—following an initial insult. Seizure incidence during the human …

Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) are
important tools in cognitive and clinical neuroscience. Combined EEG–fMRI has been …

Medically refractory focal epilepsy is potentially curable by surgery. This Review considers
the application of recent advances in structural and functional brain imaging to increase the …

Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have
proved to be extremely valuable tools for the non-invasive study of human brain function …

Simultaneous scalp EEG–fMRI measurements allow the study of epileptic networks and
more generally, of the coupling between neuronal activity and haemodynamic changes in …

Objective: Surgical treatment of focal epilepsy in patients with focal cortical dysplasia (FCD)
is most successful if all epileptogenic tissue is resected. This may not be evident on …

Background The main challenge in assessing patients with epilepsy for resective surgery is
localising seizure onset. Frequently, identification of the irritative and seizure onset zones …

The combining of electroencephalography (EEG) and functional magnetic resonance
imaging (fMRI) is a unique noninvasive method for investigating the brain regions involved …

The prevalence of epilepsy is about 1% and one-third of cases do not respond to medical
treatment. In an eligible subset of patients with drug-resistant epilepsy, surgical resection of …

The generation of interictal epileptiform discharges (IEDs) in partial epilepsies is commonly
ascribed to enhanced excitatory interactions within glutamatergic neuronal networks. Recent …