Binding of transition metal ions to albumin: sites, affinities and rates

W Bal, M Sokołowska, E Kurowska, P Faller - Biochimica et Biophysica Acta …, 2013 - Elsevier
Background Serum albumin is the most abundant protein in the blood and cerebrospinal
fluid and plays a fundamental role in the distribution of essential transition metal ions in the …

Ischemia‐modified albumin: origins and clinical implications

A Shevtsova, I Gordiienko, V Tkachenko… - Disease …, 2021 - Wiley Online Library
Albumin is one of the most abundant proteins in the body of mammals: about 40% of its pool
is located in the intravascular space and the remainder is found in the interstitial space. The …

[HTML][HTML] Towards the functional high-resolution coordination chemistry of blood plasma human serum albumin

S Al-Harthi, JI Lachowicz, ME Nowakowski… - Journal of inorganic …, 2019 - Elsevier
Human serum albumin (HSA) is a monomeric, globular, multi-carrier and the most abundant
protein in the blood. HSA displays multiple ligand binding sites with extraordinary binding …

Novel invasive and noninvasive cardiac-specific biomarkers in obesity and cardiovascular diseases

R Parsanathan, SK Jain - Metabolic syndrome and related disorders, 2020 - liebertpub.com
Cardiovascular disease (CVD) is the leading cause of fatality and disability worldwide
regardless of gender. Obesity has reached epidemic proportions in population across …

[HTML][HTML] Ischemia-modified albumin: Crosstalk between fatty acid and cobalt binding

JPC Coverdale, KGH Katundu, AIS Sobczak… - … and Essential Fatty …, 2018 - Elsevier
Myocardial ischemia is difficult to diagnose effectively with still few well-defined biochemical
markers for identification in advance, or in the absence of myocardial necrosis.“Ischemia …

Ischemia‐Modified Albumin as a Marker of Acute Coronary Syndrome: The Case for Revising the Concept of “N‐Terminal Modification” to “Fatty Acid Occupation” of …

I Oran, B Oran - Disease markers, 2017 - Wiley Online Library
Ischemia‐modified albumin (IMA) is assumed “N‐terminal modified” albumin which is
generated immediately following myocardial ischemia. The diagnosis of IMA is based on …

Is ischemia modified albumin a disease activity marker for inflammatory bowel diseases?

M Kaplan, M Yuksel, I Ates, ZMY Kilic… - Journal of …, 2016 - Wiley Online Library
Abstract Background and Aim: We aimed to identify ischemia‐modified albumin (IMA) levels
in inflammatory bowel disease (IBD) and IBD subgroups, and to examine its relation with …

A gold nanoparticles enhanced surface plasmon resonance immunosensor for highly sensitive detection of ischemia-modified albumin

G Li, X Li, M Yang, MM Chen, LC Chen, XL Xiong - Sensors, 2013 - mdpi.com
In this study a novel sensitive nanogold particle sensor enhancement based on mixed self-
assembled monolayers was explored and used to construct a Surface Plasmon Resonance …

HPLC separation of human serum albumin isoforms based on their isoelectric points

L Turell, H Botti, L Bonilla, MJ Torres, F Schopfer… - … of Chromatography B, 2014 - Elsevier
Human serum albumin (HSA) is the most abundant protein in plasma. Cys34, the only free
Cys residue, is the predominant plasma thiol and a relevant sacrificial antioxidant. Both in …

Fatty acid-mediated inhibition of metal binding to the multi-metal site on serum albumin: implications for cardiovascular disease

CA Blindauer, S Khazaipoul, R Yu… - Current Topics in …, 2016 - ingentaconnect.com
Human serum albumin (HSA) is the major protein in blood plasma and is responsible for
circulatory transport of a range of small molecules including fatty acids, metal ions and …