Skeletal muscle is composed of a large and heterogeneous assortment of cell populations
that interact with each other to maintain muscle homeostasis and orchestrate regeneration …

Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …

Neutrophils are attracted to and generate dense swarms at sites of cell damage in diverse
tissues, often extending the local disruption of organ architecture produced by the initial …

Depending on the inflammatory milieu, injury can result either in a tissue's complete
regeneration or in its degeneration and fibrosis, the latter of which could potentially lead to …

Muscle regeneration is a closely regulated process that involves a variety of cell types such
as satellite cells, myofibers, fibroadipogenic progenitors, endothelial cells, and inflammatory …

Recent discoveries reveal complex interactions between skeletal muscle and the immune
system that regulate muscle regeneration. In this review, we evaluate evidence that …

Skeletal muscle mass is subject to rapid changes according to growth stimuli inducing both
hypertrophy, through increased protein synthesis, and hyperplasia, activating the myogenic …

Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide
variety of innate and adaptive immune cells orchestrate the complex process of muscle …

Duchenne muscular dystrophy (DMD) is the most common, lethal, muscle-wasting disease
of childhood. Previous investigations have shown that muscle macrophages may play an …

Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic
inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular …