The role of malic enzyme as the provider of NADPH in oleaginous microorganisms: a reappraisal and unsolved problems

C Ratledge - Biotechnology letters, 2014 - Springer
Abstract Malic enzyme (ME; NADP+-dependent; EC 1.1. 40) provides NADPH for lipid
biosynthesis in oleaginous microorganisms. Its role in vivo depends on there being an …

Characterization of malic enzyme and the regulation of its activity and metabolic engineering on lipid production

YJ Liang, JG Jiang - RSC Advances, 2015 - pubs.rsc.org
Nowadays, microbial lipids are employed as the feedstock for biodiesel production, which
has attracted great attention across the whole world. Malic enzyme (ME) is a key enzyme …

Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production

IA Tiukova, J Brandenburg, J Blomqvist… - Biotechnology for …, 2019 - Springer
Background Rhodotorula toruloides is a promising platform organism for production of lipids
from lignocellulosic substrates. Little is known about the metabolic aspects of lipid …

Lipids of yeasts and filamentous fungi and their importance for biotechnology

V Passoth - Biotechnology of yeasts and filamentous fungi, 2017 - Springer
Lipids are essential for any organism. They are hydrophobic compounds and include, for
instance, acylglycerides, free fatty acids, sterols and isoprenoids. Their synthesis starts from …

Metabolic engineering of long chain-polyunsaturated fatty acid biosynthetic pathway in oleaginous fungus for dihomo-gamma linolenic acid production

C Chutrakul, S Jeennor, S Panchanawaporn… - Journal of …, 2016 - Elsevier
Microbial lipids are promising alternative sources of long chain-polyunsaturated fatty acids
(LC-PUFAs) for food, feed, nutraceutical and pharmaceutical sectors. Dihomo-γ-linolenic …

Specific Arabidopsis thaliana malic enzyme isoforms can provide anaplerotic pyruvate carboxylation function in Saccharomyces cerevisiae

MB Badia, R Mans, AV Lis, MA Tronconi… - The FEBS …, 2017 - Wiley Online Library
NAD (P)‐malic enzyme (NAD (P)‐ME) catalyzes the reversible oxidative decarboxylation of
malate to pyruvate, CO2, and NAD (P) H and is present as a multigene family in Arabidopsis …

Chimeric structure of plant malic enzyme family: different evolutionary scenarios for NAD-and NADP-dependent isoforms

MA Tronconi, CS Andreo, MF Drincovich - Frontiers in plant science, 2018 - frontiersin.org
Malic enzyme (ME) comprises a family of proteins with multiple isoforms located in different
compartments of eukaryotic cells. In plants, cytosolic and plastidic enzymes share several …

[HTML][HTML] Early-Stage Infection-Specific Heterobasidion annosum (Fr.) Bref. Transcripts in H. annosumPinus sylvestris L. Pathosystem

M Ramanenka, DE Ruņģis, V Šķipars - International Journal of Molecular …, 2024 - mdpi.com
Transcriptomes from stem-inoculated Scots pine saplings were analyzed to identify unique
and enriched H. annosum transcripts in the early stages of infection. Comparing different …

Reengineering lipid biosynthetic pathways of Aspergillus oryzae for enhanced production of γ-linolenic acid and dihomo-γ-linolenic acid

S Jeennor, J Anantayanon, S Panchanawaporn… - Gene, 2019 - Elsevier
Biological significance of 18-carbon polyunsaturated fatty acids, γ-linolenic acid (GLA; C18:
3 n-6) and dihomo-γ-linolenic acid (DGLA; C20: 3 n-6) has gained much attention in the …

Dissecting metabolic behavior of lipid over-producing strain of Mucor circinelloides through genome-scale metabolic network and multi-level data integration

W Vongsangnak, A Kingkaw, J Yang, Y Song… - Gene, 2018 - Elsevier
Lipid accumulation is an important cellular process of oleaginous microorganisms. To
dissect metabolic behavior of oleaginous Zygomycetes, the lipid over-producing strain …