Microtubules are highly dynamic structures, which consist of α-and β-tubulin heterodimers,
and are involved in cell movement, intracellular trafficking, and mitosis. In the context of …

Given the problems with malignant cancer cells showing innate and acquired resistance to
apoptosis, we need alternative means to induce cell death in cancer. Paraptosis is a type of …

Thymoquinone (TQ), a component of black seed essential oil, is known to induce apoptotic
cell death and oxidative stress, however, the direct involvement of oxidants in TQ-induced …

Tubulin proteins, as components of the microtubule cytoskeleton perform critical cellular
functions throughout all phases of the cell cycle. Altered tubulin isotype composition of …

An ever-increasing number of studies highlight the role of uncoupling protein 2 (UCP2) in a
broad range of physiological and pathological processes. The knowledge of the molecular …

Combining chemotherapeutics is a promising method of improving cancer treatment;
however, the clinical success of combination therapy is limited by the distinct …

The apoptosis of cancer cells is associated with changes in the important cell properties
including morphology, surface roughness and stiffness. Therefore, the changes in …

Chemotherapy‐induced neuropathic pain is a debilitating and common side effect of cancer
treatment. Mitochondrial dysfunction associated with oxidative stress in peripheral nerves …

Generally, both endoplasmic reticulum (ER) stress and mitochondrial dysregulation are a
potential therapeutic target of anticancer agents including bortezomib. The treatment of …

Previous studies have demonstrated that mesenchymal stromal cells (MSCs) enhance cell
survival through upregulation and secretion of stanniocalcin-1 (STC1). This study shows that …