[HTML][HTML] Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

TM Uddin, AJ Chakraborty, A Khusro… - Journal of infection and …, 2021 - Elsevier
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

Machine learning for microbiologists

F Asnicar, AM Thomas, A Passerini… - Nature Reviews …, 2024 - nature.com
Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …

Accelerating antibiotic discovery through artificial intelligence

MCR Melo, JRMA Maasch… - Communications …, 2021 - nature.com
By targeting invasive organisms, antibiotics insert themselves into the ancient struggle of the
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …

Genome-based prediction of bacterial antibiotic resistance

M Su, SW Satola, TD Read - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …

Machine learning for antimicrobial resistance prediction: current practice, limitations, and clinical perspective

JI Kim, F Maguire, KK Tsang, T Gouliouris… - Clinical microbiology …, 2022 - Am Soc Microbiol
Antimicrobial resistance (AMR) is a global health crisis that poses a great threat to modern
medicine. Effective prevention strategies are urgently required to slow the emergence and …

Prediction of antimicrobial resistance based on whole-genome sequencing and machine learning

Y Ren, T Chakraborty, S Doijad, L Falgenhauer… - …, 2022 - academic.oup.com
Motivation Antimicrobial resistance (AMR) is one of the biggest global problems threatening
human and animal health. Rapid and accurate AMR diagnostic methods are thus very …

A fast and agnostic method for bacterial genome-wide association studies: Bridging the gap between k-mers and genetic events

M Jaillard, L Lima, M Tournoud, P Mahé… - PLoS …, 2018 - journals.plos.org
Genome-wide association study (GWAS) methods applied to bacterial genomes have
shown promising results for genetic marker discovery or detailed assessment of marker …

Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals

N Puvača, R de Llanos Frutos - Antibiotics, 2021 - mdpi.com
Throughout scientific literature, we can find evidence that antimicrobial resistance has
become a big problem in the recent years on a global scale. Public healthcare systems all …

Artificial intelligence and machine learning assisted drug delivery for effective treatment of infectious diseases

S He, LG Leanse, Y Feng - Advanced Drug Delivery Reviews, 2021 - Elsevier
In the era of antimicrobial resistance, the prevalence of multidrug-resistant microorganisms
that resist conventional antibiotic treatment has steadily increased. Thus, it is now …

Large-scale assessment of antimicrobial resistance marker databases for genetic phenotype prediction: a systematic review

N Mahfouz, I Ferreira, S Beisken… - Journal of …, 2020 - academic.oup.com
Background Antimicrobial resistance (AMR) is a rising health threat with 10 million annual
casualties estimated by 2050. Appropriate treatment of infectious diseases with the right …