[PDF][PDF] Pan-cancer integrative histology-genomic analysis via multimodal deep learning

RJ Chen, MY Lu, DFK Williamson, TY Chen, J Lipkova… - Cancer Cell, 2022 - cell.com
The rapidly emerging field of computational pathology has demonstrated promise in
developing objective prognostic models from histology images. However, most prognostic …

Prognostic analysis of cuproptosis-related gene in triple-negative breast cancer

S Sha, L Si, X Wu, Y Chen, H Xiong, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Background Cuproptosis is a copper-dependent cell death mechanism that is associated
with tumor progression, prognosis, and immune response. However, the potential role of …

The landscape of tumor-specific antigens in colorectal cancer

NAA Rus Bakarurraini, NS Ab Mutalib, R Jamal, N Abu - Vaccines, 2020 - mdpi.com
Over the last few decades, major efforts in cancer research and treatment have intensified.
Apart from standard chemotherapy approaches, immunotherapy has gained substantial …

[HTML][HTML] Identification of the prognostic significance of somatic mutation-derived LncRNA signatures of genomic instability in lung adenocarcinoma

W Geng, Z Lv, J Fan, J Xu, K Mao, Z Yin… - Frontiers in cell and …, 2021 - frontiersin.org
Background: Lung adenocarcinoma (LUAD) is a highly heterogeneous tumor with
substantial somatic mutations and genome instability, which are emerging hallmarks of …

A novel prognostic index of stomach adenocarcinoma based on immunogenomic landscape analysis and immunotherapy options

W Xue, B Dong, Y Wang, Y Xie, P Li, Z Gong… - … and Molecular Pathology, 2022 - Elsevier
Stomach adenocarcinoma (STAD) is one of the most common malignant tumors worldwide.
In this study, we attempted to construct a valid immune-associated gene prognostic index …

TTN mutations predict a poor prognosis in patients with thyroid cancer

X Han, J Chen, J Wang, J Xu, Y Liu - Bioscience Reports, 2022 - portlandpress.com
Objective: We aimed to investigate the relationship between titin (TTN) gene mutations and
thyroid cancer (THCA) and to explore the feasibility of the TTN gene as a potential …

[HTML][HTML] LRP1B mutation: a novel independent prognostic factor and a predictive tumor mutation burden in hepatocellular carcinoma

F Liu, W Hou, J Liang, L Zhu, C Luo - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common malignancies globally and the
second leading cause of cancer-related death. Low-density lipoprotein (LDL) receptor …

Immuno-genomic classification of colorectal cancer organoids reveals cancer cells with intrinsic immunogenic properties associated with patient survival

EJ Cho, M Kim, D Jo, J Kim, JH Oh, HC Chung… - Journal of Experimental …, 2021 - Springer
Background The intrinsic immuno-ge7nomic characteristics of colorectal cancer cells that
affect tumor biology and shape the tumor immune microenvironment (TIM) are unclear …

[HTML][HTML] M6A classification combined with tumor microenvironment immune characteristics analysis of bladder cancer

H Zhu, X Jia, Y Wang, Z Song, N Wang, Y Yang… - Frontiers in …, 2021 - frontiersin.org
Background Studies have shown that N6-methyl adenosine (m6A) plays an important role in
cancer progression; however, the underlying mechanism of m6A modification in tumor …

Cuproptosis-related lncRNAs predict the prognosis and immune response in hepatocellular carcinoma

Q Zhang, Y Huang, Y Xia, Y Liu, J Gan - Clinical and Experimental …, 2023 - Springer
Cuproptosis has been recently used to indicate unique biological processes triggered by Cu
action as a new term. This study aimed to explore the relationship between cuproptosis …