This narrative review aims to discuss the more relevant evidence on the role of linoleic acid
(LA), a n-6 essential fatty acid that constitutes the predominant proportion of dietary …

Since its identification in 2000, the interest of scientists in the hepatokine fibroblast growth
factor (FGF) 21 has tremendously grown, and still remains high, due to a wealth of very …

Context Saturated fatty acid (SFA) vs polyunsaturated fatty acid (PUFA) may promote
nonalcoholic fatty liver disease by yet unclear mechanisms. Objective To investigate if …

Among the polyunsaturated fatty acids (PUFAs), those belonging to the n-3 (or ω3) series, ie,
alpha-linolenic (ALA), eicosapentaenoic (EPA), and docosahexaenoic (DHA) acids have …

Background The consumption of a Western-style diet (WSD) and high fructose intake are
risk factors for metabolic diseases. The underlying mechanisms are largely unclear …

The aim of this network meta-analysis (NMA) is to compare the effects of different oils/solid
fats on blood lipids. Literature searches were performed until March 2018. Inclusion criteria …

Background: Dietary fat composition can affect ectopic lipid accumulation and, thereby,
insulin resistance. Diets that are high in saturated fatty acids (SFAs) or polyunsaturated fatty …

Non-alcoholic fatty liver disease (NAFLD) is a growing epidemic, in parallel with the obesity
crisis, rapidly becoming one of the commonest causes of chronic liver disease worldwide …

Lifestyle factors conferring increased diabetes risk are associated with elevated basal
insulin levels (hyperinsulinaemia). The latter predicts later obesity in children and …

This systematic review has examined more than 300 original papers dealing with the
biology of overfeeding. Studies have varied from 1 day to 6 months. Overfeeding produced …