[HTML][HTML] The mechanism of sudden unexpected death in epilepsy: A mini review

X Sun, Y Lv, J Lin - Frontiers in neurology, 2023 - frontiersin.org
Sudden unexpected death in epilepsy (SUDEP) is defined as a sudden, unexpected, non-
traumatic, non-drowning death in a person with epilepsy. SUDEP is generally considered to …

Revealing the precise role of calretinin neurons in epilepsy: we are on the way

Y Qi, H Cheng, Y Wang, Z Chen - Neuroscience Bulletin, 2022 - Springer
Epilepsy is a common neurological disorder characterized by hyperexcitability in the brain.
Its pathogenesis is classically associated with an imbalance of excitatory and inhibitory …

[HTML][HTML] Kv1.1 channels mediate network excitability and feed-forward inhibition in local amygdala circuits

S Thouta, Y Zhang, E Garcia, TP Snutch - Scientific Reports, 2021 - nature.com
Kv1. 1 containing potassium channels play crucial roles towards dampening neuronal
excitability. Mice lacking Kv1. 1 subunits (Kcna1−/−) display recurrent spontaneous seizures …

[HTML][HTML] The role of sleep state and time of day in modulating breathing in epilepsy: implications for sudden unexpected death in epilepsy

KG Joyal, BL Kreitlow, GF Buchanan - Frontiers in neural circuits, 2022 - frontiersin.org
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among
patients with refractory epilepsy. While the exact etiology of SUDEP is unknown, mounting …

[HTML][HTML] Respiratory entrainment of the locus coeruleus modulates arousal level to avoid physical risks from external vibration

M Iwamoto, S Yonekura, N Atsumi, S Hirabayashi… - Scientific Reports, 2023 - nature.com
Slow rocking chairs can easily put people to sleep, while violent shaking, such as during
earthquakes, may lead to rapid awakening. However, the influence of external body …

[HTML][HTML] Perspectives on the basis of seizure-induced respiratory dysfunction

DK Mulkey, BM Milla - Frontiers in Neural Circuits, 2022 - frontiersin.org
Epilepsy is an umbrella term used to define a wide variety of seizure disorders and sudden
unexpected death in epilepsy (SUDEP) is the leading cause of death in epilepsy. Although …

Neuropeptide depletion in the amygdala in sudden unexpected death in epilepsy: A postmortem study

A Somani, C Perry, S Patodia, Z Michalak, M Ellis… - …, 2020 - Wiley Online Library
Objective Sudden unexpected death in epilepsy (SUDEP) is typically unwitnessed but can
be preceded by seizures in the period prior to death. Peri‐ictal respiratory dysfunction is a …

Limbic and paralimbic respiratory modulation: from inhibition to enhancement

G Chaitanya, JP Hampson, E Toth, NJ Hupp… - …, 2022 - Wiley Online Library
Objective Increased understanding of the role of cortical structures in respiratory control may
help the understanding of seizure‐induced respiratory dysfunction that leads to sudden …

Inhibition of hyperactivity of the dorsal raphe 5‐HTergic neurons ameliorates hippocampal seizure

H Cheng, Y Qi, N Lai, L Yang, C Xu… - CNS Neuroscience …, 2021 - Wiley Online Library
Aims Epilepsy, frequently comorbid with depression, easily develops drug resistance. Here,
we investigated how dorsal raphe (DR) and its 5‐HTergic neurons are implicated in …

The diverse role of the raphe 5-HTergic systems in epilepsy

H Cheng, C Gao, Q Lou, Z Chen, Y Wang - Acta Pharmacologica Sinica, 2022 - nature.com
The raphe nuclei comprise nearly all of 5-hydroxytryptaminergic (5-HTergic) neurons in the
brain and are widely acknowledged to participate in the modulation of neural …