Toxicopathological and immunological studies on different concentrations of chitosan-coated silver nanoparticles in rats

EI Hassanen, AA Khalaf, AF Tohamy… - International journal …, 2019 - Taylor & Francis
Background Much consideration has been paid to the toxicological assessment of
nanoparticles prior to clinical and biological applications. While in vitro studies have been …

Cisplatin-induced azoospermia and testicular damage ameliorated by adipose-derived mesenchymal stem cells

HY Ismail, NA Shaker, S Hussein, A Tohamy, M Fathi… - Biological Research, 2023 - Springer
Background The testes are highly susceptible to the adverse effects of chemotherapy and
radiation at all stages of life. Exposure to these threats mainly occurs during cancer …

Combination of metformin and luteolin synergistically protects carbon tetrachloride‐induced hepatotoxicity: Mechanism involves antioxidant, anti‐inflammatory …

Y Yan, C Jun, Y Lu, S Jiangmei - Biofactors, 2019 - Wiley Online Library
Liver diseases are one of the fatal disorders due to the vital role of the liver. Carbon
tetrachloride (CCl4) is the most perceived chemical substance utilized in developing models …

Evaluation of anti-inflammatory activity of Justicia secunda Vahl leaf extract using in vitro and in vivo inflammation models

GN Anyasor, AA Okanlawon, B Ogunbiyi - Clinical Phytoscience, 2019 - Springer
Abstract Background Justicia secunda Vahl. is a medicinal plant used in ethnomedical
practice as therapy to manage inflammation. Therefore, this study was designed to evaluate …

Chemical Composition of Tagetes patula Flowers Essential Oil and Hepato-Therapeutic Effect against Carbon Tetrachloride-Induced Toxicity (In-Vivo)

HY Aati, M Emam, J Al-Qahtani, S Aati, A Aati… - Molecules, 2022 - mdpi.com
The liver is a crucial organ among body organs due to its wide functions, in particular,
detoxification and metabolism. Exposure to detrimental chemicals or viral infections may …

In Vivo Antihypertensive Activity and UHPLC-Orbitrap-HRMS Profiling of Cuphea ignea A. DC.

WM Ismail, SM Ezzat, AEMK El-Mosallamy… - ACS …, 2022 - ACS Publications
Cuphea ignea A. DC. is an ornamental tropical plant belonging to the family Lythraceae. The
aim of this study is to verify the in vivo antihypertensive potential of C. ignea A. DC. and to …

Investigation of polyphenol profile, antioxidant activity and hepatoprotective potential of Aconogonon alpinum (All.) Schur roots

MZ Khan, MI Shabbir, Z Saqib, SA Gilani… - Open …, 2020 - degruyter.com
Liver plays vital role in detoxification of exogenous and endogenous chemicals. These
chemicals as well as oxidative stress may cause liver disorders. This study was aimed to …

The mollifying effect of Sambucus nigra extract on StAR gene expression, oxidative stress, and apoptosis induced by Fenpropathrin in male rats

MS Nashed, EI Hassanen, MY Issa, AF Tohamy… - Food and Chemical …, 2024 - Elsevier
Fenpropathrin (FNP) is a man-made insecticide of to the pyrethroid class, commonly
employed in agricultural and horticultural practices. However, it has a prolonged persistence …

[HTML][HTML] The hepatoprotective candidates by synergistic formula of marine and terrestrial against Acetaminophen toxicity using in-vitro, in-vivo, and in silico screening …

A Nabil-Adam, ML Ashour, MA Shreadah - Saudi Journal of Biological …, 2023 - Elsevier
Background One of the most regularly used hepatotoxic medicines is paracetamol
(acetaminophen, N-acetyl-p-aminophenol; APAP). It causes liver failure in overdoses but is …

[HTML][HTML] Lucrative antioxidant effect of metformin against cyclophosphamide induced nephrotoxicity

AF Tohamy, S Hussein, IM Moussa, H Rizk… - Saudi Journal of …, 2021 - Elsevier
Cyclophosphamide is anticancer drug with a well-Known nephrotoxicity. This work was
applied to study the lucrative antioxidant influence of metformin as co-therapy on the …