The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis
SUMMARY Human alphaherpesvirus 1 (HSV-1) is a highly successful neurotropic pathogen
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …
The perspectives of NETosis on the progression of obesity and obesity-related diseases: mechanisms and applications
J Li, L Yin, S Chen, Z Li, J Ding, J Wu… - Frontiers in Cell and …, 2023 - frontiersin.org
Obesity is a disease commonly associated with urbanization and can also be characterized
as a systemic, chronic metabolic condition resulting from an imbalance between energy …
as a systemic, chronic metabolic condition resulting from an imbalance between energy …
[HTML][HTML] Neutrophils in ocular diseases
Neutrophils, traditionally viewed as first responders to infection or tissue damage, exhibit
dynamic and diverse roles in ocular health and disease. This review elaborates on previous …
dynamic and diverse roles in ocular health and disease. This review elaborates on previous …
Emerging drugs for the treatment of herpetic keratitis
Introduction Herpes simplex keratitis stands as a prominent factor contributing to infectious
blindness among developed nations. On a global scale, over 60% of the population tests …
blindness among developed nations. On a global scale, over 60% of the population tests …
Neutrophil PPIF exacerbates lung ischemia–reperfusion injury after lung transplantation by promoting calcium overload-induced neutrophil extracellular traps …
W Wu, F Meng, H Zhang, H Tian, X Zhang - International …, 2024 - Elsevier
Lung ischemia–reperfusion (I/R) injury is the main risk factor for primary graft dysfunction
and patient death after lung transplantation (LTx). It is widely accepted that the main …
and patient death after lung transplantation (LTx). It is widely accepted that the main …
[HTML][HTML] Rapid NETosis is an effector mechanism to combat ocular herpes infection
Purpose: Neutrophils are known mediators of innate immunity, yet their effector function in
herpesvirus infections remains poorly understood. Here, we elucidate the mechanistic action …
herpesvirus infections remains poorly understood. Here, we elucidate the mechanistic action …
[HTML][HTML] Exploring heparanase levels in tears: insights from herpes simplex virus-1 keratitis patients and animal studies
Purpose: Heparanase (HPSE) cleaves heparan sulfate proteoglycans during herpes
simplex virus-1 (HSV-1) infection, aiding in viral egress and disease progression. Its action …
simplex virus-1 (HSV-1) infection, aiding in viral egress and disease progression. Its action …
[HTML][HTML] HerpDock: A GUI-based gateway to HSV-1 molecular docking insights
Abstract Herpes Simplex Virus 1 (HSV-1) is a member of the alpha-Herpesviridae family,
with over 60% of the global population being seropositive. HSV-1 can cause a range of …
with over 60% of the global population being seropositive. HSV-1 can cause a range of …
The role of neutrophil extracellular traps in Crohn's disease
Y Liu, H Deng, J Yao, C He, J Zhang - Heliyon, 2024 - cell.com
Crohn's disease (CD) is an idiopathic and chronic inflammation of the gastrointestinal (GI)
tract. The underlying pathogenesis of CD is multifaceted, with complex interactions between …
tract. The underlying pathogenesis of CD is multifaceted, with complex interactions between …
[HTML][HTML] 中性粒细胞胞外诱捕网与细菌相互作用机制的研究进展
龚亚婷， 曹宇， 吴淑燕， 黄瑞 - 2023 - jmi.fudan.edu.cn
在抗感染免疫过程中, 中性粒细胞可通过释放中性粒细胞胞外诱捕网(neutrophil extracellular
trap, NET) 捕获并杀伤病原体.NET 是一把“双刃剑”, 一方面可维持机体稳态, 另一方面NET …
trap, NET) 捕获并杀伤病原体.NET 是一把“双刃剑”, 一方面可维持机体稳态, 另一方面NET …