Simulated moving bed chromatography for the separation of enantiomers

A Rajendran, G Paredes, M Mazzotti - Journal of Chromatography A, 2009 - Elsevier
Simulated moving bed (SMB) chromatography, a continuous multi-column chromatographic
process, has become one of the preferred techniques for the separation of the enantiomers …

Advanced operating strategies to extend the applications of simulated moving bed chromatography

KM Kim, JW Lee, S Kim… - Chemical …, 2017 - Wiley Online Library
Chromatographic separation with solid stationary and fluid mobile phases is widely used to
isolate and purify compounds. One of the most productive improvements in preparative …

Understanding and revamping of industrial scale SMB units for p‐xylene separation

M Minceva, AE Rodrigues - AIChE journal, 2007 - Wiley Online Library
One of the first applications of Simulated Moving Bed (SMB) technology was in p‐xylene
recovery from mixed xylenes. The three main industrial processes for p‐xylene separation …

Modeling and Simulation of a Simulated Moving Bed for the Separation of p-Xylene

M Minceva, AE Rodrigues - Industrial & engineering chemistry …, 2002 - ACS Publications
The industrial-scale adsorptive separation of p-xylene from a mixture of C8 aromatics in a
four-section simulated moving bed (SMB) unit is analyzed through simulation. In the order to …

Fructose–glucose separation in a SMB pilot unit: modeling, simulation, design, and operation

DCS Azevedo, AE Rodrigues - AIChE journal, 2001 - Wiley Online Library
Glucose was separated from fructose experimentally using a simulated moving‐bed (SMB)
adsorber. A strongly acid cationic resin of gel type (Ca2+ form) Dowex Monosphere (dp …

Simulated moving bed chromatography: from concept to proof‐of‐concept

P Sá Gomes, AE Rodrigues - Chemical engineering & …, 2012 - Wiley Online Library
This work presents a comprehensive insight about simulated moving bed (SMB) technology,
from concept to unit operation and process demonstration. A particular relevance is given to …

Simulated moving bed technology: old and new

P Sá Gomes, M Minceva, AE Rodrigues - Adsorption, 2006 - Springer
Abstract The Simulated Moving Bed (SMB) concept has been applied to the separation of
different mixtures as a continuous counter current separation process, avoiding several …

A numerical modelling study of SO2 adsorption on activated carbons with new rate equations

Z Li, Y Liu, H Wang, CJ Tsai, X Yang, Y Xing… - Chemical Engineering …, 2018 - Elsevier
Modelling dynamic adsorption of sulfur dioxide (SO 2) on activated carbons (ACs) is
significant in guiding practical desulphurization processes and making highly efficient use of …

Design methodology and operation of a simulated moving bed reactor for the inversion of sucrose and glucose–fructose separation

DCS Azevedo, AE Rodrigues - Chemical Engineering Journal, 2001 - Elsevier
This work presents a detailed mathematical model and design methodology for a simulated
moving bed reactor (SMBR) intended to invert sucrose by enzymatic action and …

Standing wave design and experimental validation of a tandem simulated moving bed process for insulin purification

Y Xie, S Mun, J Kim, NHL Wang - Biotechnology progress, 2002 - Wiley Online Library
A tandem simulated moving bed (SMB) process for insulin purification has been proposed
and validated experimentally. The mixture to be separated consists of insulin, high …