[HTML][HTML] Zoonosis and zooanthroponosis of emerging respiratory viruses
AM Khalil, L Martinez-Sobrido… - Frontiers in Cellular and …, 2024 - frontiersin.org
Lung infections in Influenza-Like Illness (ILI) are triggered by a variety of respiratory viruses.
All human pandemics have been caused by the members of two major virus families …
All human pandemics have been caused by the members of two major virus families …
[HTML][HTML] Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations
Influenza virus continuously evolves to escape human adaptive immunity and generates
seasonal epidemics. Therefore, influenza vaccine strains need to be updated annually for …
seasonal epidemics. Therefore, influenza vaccine strains need to be updated annually for …
[HTML][HTML] Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin
The receptor-binding site of influenza A virus hemagglutinin partially overlaps with major
antigenic sites and constantly evolves. In this study, we observe that mutations G186D and …
antigenic sites and constantly evolves. In this study, we observe that mutations G186D and …
Hemagglutinin destabilization in H3N2 vaccine reference viruses skews antigenicity and prevents airborne transmission in ferrets
During influenza virus entry, the hemagglutinin (HA) protein binds receptors and causes
membrane fusion after endosomal acid activation. To improve vaccine efficiency and …
membrane fusion after endosomal acid activation. To improve vaccine efficiency and …
[HTML][HTML] Seasonal antigenic prediction of influenza A H3N2 using machine learning
Antigenic characterization of circulating influenza A virus (IAV) isolates is routinely assessed
by using the hemagglutination inhibition (HI) assays for surveillance purposes. It is also …
by using the hemagglutination inhibition (HI) assays for surveillance purposes. It is also …
Neutralizing antibody responses against contemporary and future influenza A (H3N2) viruses in paradoxical clades elicited by repeated and single vaccinations
T Zhang, Y Han, W Huang, H Wei… - Journal of Medical …, 2024 - Wiley Online Library
As one of the most effective measures to prevent seasonal influenza viruses, annual
influenza vaccination is globally recommended. Nevertheless, evidence regarding the …
influenza vaccination is globally recommended. Nevertheless, evidence regarding the …
Lack of neutralizing antibodies against the current circulating influenza viruses during the Omicron outbreak in Hong Kong
W Liang, H Lv, C Chen, Y Sun, DS Hui, CK Pun Mok - bioRxiv, 2023 - biorxiv.org
We report the seroprevalence to the circulating influenza A H1N1 and H3N2 viruses from
plasma samples collected from 479 adults between 2021 and 2022. Our results show that …
plasma samples collected from 479 adults between 2021 and 2022. Our results show that …
[PDF][PDF] Influenza A Virus: From Infection to Prevention. Long-term Effects of an Early Life IAV Infection in vivo and Optimization of the Live Attenuated Influenza A …
JP PEREIRA BONIFACIO LOPES - scholar.archive.org
Influenza A virus (IAV) is one of the major causative agents of acute respiratory infections in
humans. Influenza disease causes up to 650,000 deaths every year with its burden highest …
humans. Influenza disease causes up to 650,000 deaths every year with its burden highest …
[PDF][PDF] Influenza A Virus: From Infection to Prevention. Long-term Effects of an Early Life IAV Infection in vivo and Optimization of the Live Attenuated Influenza A …
JPPB LOPES - access.archive-ouverte.unige.ch
Influenza A virus (IAV) is one of the major causative agents of acute respiratory infections in
humans. Influenza disease causes up to 650,000 deaths every year with its burden highest …
humans. Influenza disease causes up to 650,000 deaths every year with its burden highest …
Antigenic Effects of Influenza A (H3n2) Virus Egg-Adaptation Substitutions are Influenced by Evolution Associated Substitutions
AJ Hadiprodjo, YY Tseng, L Carolan… - Available at SSRN … - papers.ssrn.com
Influenza vaccine viruses are predominantly grown in embryonated hens-eggs. A (H3N2)
viruses commonly adapt to growth in eggs by substituting hemagglutinin positions G186V or …
viruses commonly adapt to growth in eggs by substituting hemagglutinin positions G186V or …