Impairments in systematic and regional glucose metabolism exist in patients with
Parkinson's disease (PD) at every stage of the disease course, and such impairments are …

Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and prion diseases, are
directly linked to the formation and accumulation of protein aggregates in the brain. These …

Protein aggregation is a complex physiological process, primarily determined by stress-
related factors revealing the hidden aggregation propensity of proteins that otherwise are …

The deposition of proteins in the form of insoluble amyloid fibril aggregates is linked to a
range of diseases. The supramolecular architecture of such deposits is governed by the …

To date, the mechanisms of biomineralization induced by bacterial cells in the context of
biofilm formation remain the subject of intensive studies. In this study, we analyzed the …

Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a ubiquitous enzyme that
catalyzes the sixth step of glycolysis and thus, serves to break down glucose for energy …

Hesperidin (HESP), a flavanone glycoside, shows high antioxidant properties and posses
ability to go through the blood–brain barrier. Therefore, it could be a potential drug molecule …

The role of nucleic acids in protein folding and aggregation is an area of continued research,
with relevance to understanding both basic biological processes and disease. In this review …

Polysaccharides, being biocompatible and biodegradable polymers, are highly attractive as
materials for protein delivery systems. However, protein–polysaccharide interactions may …

In many neurodegenerative diseases, formation of protein fibrillar aggregates has been
observed as a major pathological change. Neurofibrillary tangles, mainly composed of fibrils …