Leptospirosis is the most wide spread zoonosis worldwide; it is present in all continents
except Antarctica and evidence for the carriage of Leptospira has been found in virtually all …

Leptospirosis is a zoonotic disease that has emerged as an important cause of morbidity
and mortality among impoverished populations. One hundred years after the discovery of …

Globally, leptospirosis poses an increasing public health problem, as evidenced by
markedly increasing incidence rates and multiple outbreaks in all continents. Yet, the …

Leptospirosis is a devastating zoonotic disease affecting people and animals across the
globe. Pathogenic leptospires are excreted in urine of reservoir hosts which directly or …

Due to the complex and dynamic epidemiology of leptospirosis on livestock, control is still
controversial and frustrating. In this context, this paper discusses the main challenges and …

Although the widespread use of artificial insemination has made it possible to breed cattle
with minimal risk of transmitting specific venereal pathogens, sexually transmitted diseases …

The molecular and cellular pathogenesis of leptospirosis remains poorly understood. Based
on comparative bacterial genomics data, we recently identified the hypothetical PF07598 …

Infertility is the diminished or absent capacity to produce viable offspring. Infections that
reduce ovulation rates, fertilization rates, embryonic survival rates, fetal survival rates or …

It is well known that Leptospira vaccine prevents the disease. However specificity for
serovars limits the efficacy of killed whole cell vaccines. Leptospiral antigens that induce …

We previously reported the cloning and characterization of leptospiral immunoglobulin-like
proteins LigA and LigB of Leptospira interrogans. LigA and LigB are conserved at the amino …