Evaluating endoplasmic reticulum stress and unfolded protein response through the lens of ecology and evolution
Considerable progress has been made in understanding the physiological basis for
variation in the life‐history patterns of animals, particularly with regard to the roles of …
variation in the life‐history patterns of animals, particularly with regard to the roles of …
Beneficial effects of CCL8 inhibition at lipopolysaccharide-induced lung injury
Summary CCL8 (MCP-2) is a chemoattractive cytokine associated with various immune-
related pathologies. Recent studies show that CCL8 is significantly stimulated during acute …
related pathologies. Recent studies show that CCL8 is significantly stimulated during acute …
Growth hormone releasing hormone in the unfolded protein response context
N Barabutis - Endocrine, 2020 - Springer
Abstract The effects of Growth Hormone Releasing Hormone in human pathophysiology are
not limited to those mediated by the Growth Hormone Releasing Hormone–Growth …
not limited to those mediated by the Growth Hormone Releasing Hormone–Growth …
Coordination analysis of gene expression points to the relative impact of different regulators during endoplasmic reticulum stress
Y Zhang, MD Lucius, D Altomare, A Havighorst… - DNA and Cell …, 2019 - liebertpub.com
Analysis of gene expression can be challenging, especially if it involves genetically diverse
populations that exhibit high variation in their individual expression profile. Despite this …
populations that exhibit high variation in their individual expression profile. Despite this …
[HTML][HTML] Identification of frailty-associated genes by coordination analysis of gene expression
Differential expression analyses provide powerful tools for the identification of genes playing
a role in disease pathogenesis. Yet, such approaches are usually restricted by the high …
a role in disease pathogenesis. Yet, such approaches are usually restricted by the high …
Coordination in the unfolded protein response during aging in outbred deer mice
Endoplasmic reticulum (ER) stress has been linked to various metabolic pathologies,
neurodegeneration and aging. Although various mechanistic aspects of the resulting …
neurodegeneration and aging. Although various mechanistic aspects of the resulting …
Propensity to endoplasmic reticulum stress in deer mouse fibroblasts predicts skin inflammation and body weight gain
Y Zhang, C Lim, V Sikirzhytski… - Disease Models & …, 2021 - journals.biologists.com
The unfolded protein response (UPR) is involved in the pathogenesis of metabolic
disorders, yet whether variations in the UPR among individuals influence the propensity for …
disorders, yet whether variations in the UPR among individuals influence the propensity for …
Transcriptomic coordination at hepatic steatosis indicates robust immune cell engagement prior to inflammation
Background Deregulation in lipid metabolism leads to the onset of hepatic steatosis while at
subsequent stages of disease development, the induction of inflammation, marks the …
subsequent stages of disease development, the induction of inflammation, marks the …
A weak response to endoplasmic reticulum stress is associated with postoperative organ failure in patients undergoing cardiac surgery with cardiopulmonary bypass
T Clavier, Z Demailly, X Semaille, C Thill, J Selim… - Frontiers in …, 2021 - frontiersin.org
Introduction: Endoplasmic reticulum stress (ERS) is involved in inflammatory organ failure.
Our objective was to describe ERS, its unfolded protein response (UPR) expression/kinetics …
Our objective was to describe ERS, its unfolded protein response (UPR) expression/kinetics …
Genomic variation in captive deer mouse (Peromyscus maniculatus) populations
Abstract Background Deer mice (genus Peromyscus) are the most common rodents in North
America. Despite the availability of reference genomes for some species, a comprehensive …
America. Despite the availability of reference genomes for some species, a comprehensive …