Mechanical forces are able to activate hypertrophic growth of cardiomyocytes in the
overloaded myocardium. However, the transcriptional profiles triggered by mechanical …

Background: Mammalian WD-repeat protein 12 (WDR12), a family member of proteins
containing repeats of tryptophan-aspartic acid (WD), is a potential homolog of yeast Ytm1p …

The synthesis of eukaryotic ribosomes is a complex, energetically demanding process
requiring the aid of numerous non-ribosomal factors, such as the PeBoW complex. The …

Exploring and discovering novel circRNAs is one of the ways to develop innovative drugs for
the diagnosis and treatment of myocardial ischemia-reperfusion injury (MI/RI). In the work …

Glioblastoma (GBM) is the most malignant primary brain tumor in adults. Due to its invasive
nature, it cannot be thoroughly eliminated. WD repeat domain 12 (WDR12) processes the …

In this study, we investigated whether local intramyocardial GATA4 overexpression affects
the left ventricular (LV) remodelling process and the importance of phosphorylation at serine …

Objectives: Ambulatory systolic-diastolic pressure regression index (ASDPRI) as a
composite marker of cardiovascular (CV) properties is related to CV complications …

摘要目的探究敲低WD 重复结构域12 (WDR12) 对小鼠精原细胞(GC-1) 的影响.
方法利用脂质体转染法将针对WDR12 的shRNA 编码克隆(shWDR12) 及阴性对照的EGFP …

La biogénesis ribosomal es uno de los procesos más complejos, esenciales y costosos
energéticamente de la célula eucariota. La formación de las subunidades ribosomales en …

Cardiomyopathies are the most common form of genetic disorders featuring primary
abnormalities in the structure and function of the heart. Over the past few decades …