[PDF][PDF] Somatic cell nuclear transfer reprogramming: mechanisms and applications

S Matoba, Y Zhang - Cell stem cell, 2018 - cell.com
Successful cloning of monkeys, the first non-human primate species, by somatic cell nuclear
transfer (SCNT) attracted worldwide attention earlier this year. Remarkably, it has taken …

Extranuclear inheritance of mitochondrial genome and epigenetic reprogrammability of chromosomal telomeres in somatic cell cloning of mammals

M Samiec, M Skrzyszowska - International Journal of Molecular Sciences, 2021 - mdpi.com
The effectiveness of somatic cell nuclear transfer (SCNT) in mammals seems to be still
characterized by the disappointingly low rates of cloned embryos, fetuses, and progeny …

Rewinding the process of mammalian extinction

J Saragusty, S Diecke, M Drukker, B Durrant… - Zoo …, 2016 - Wiley Online Library
With only three living individuals left on this planet, the northern white rhinoceros
(Ceratotherium simum cottoni) could be considered doomed for extinction. It might still be …

Reduction, proliferation, and differentiation defects of stem cells over time: a consequence of selective accumulation of old centrioles in the stem cells?

J Tkemaladze - Molecular Biology Reports, 2023 - Springer
Background All molecules, structures, cells in organisms are subjected to destruction during
the process of vital activities. In the organisms of most multicellular animals and humans, the …

First cloned Bactrian camel (Camelus bactrianus) calf produced by interspecies somatic cell nuclear transfer: A step towards preserving the critically endangered wild …

NA Wani, BS Vettical, SB Hong - PloS one, 2017 - journals.plos.org
Studies were conducted to explore the possibility of employing dromedary camel (Camelus
dromedarius) oocytes as recipient cytoplasts for the development of interspecies somatic …

Molecular mechanism and application of somatic cell cloning in mammals—Past, present and future

M Samiec - International Journal of Molecular Sciences, 2022 - mdpi.com
Thus far, nearly 25 mammalian species have been cloned by intra-or interspecies somatic
cell nuclear transfer (SCNT). Among them, non-transgenic and transgenic representatives of …

Cloning in action: can embryo splitting, induced pluripotency and somatic cell nuclear transfer contribute to endangered species conservation?

A Swegen, R Appeltant, SA Williams - Biological Reviews, 2023 - Wiley Online Library
The term 'cloning'refers to the production of genetically identical individuals but has meant
different things throughout the history of science: a natural means of reproduction in …

A road map for 21st century genetic restoration: gene pool enrichment of the black-footed ferret

SM Wisely, OA Ryder, RM Santymire… - Journal of …, 2015 - academic.oup.com
Interspecies somatic cell nuclear transfer (iSCNT) could benefit recovery programs of
critically endangered species but must be weighed with the risks of failure. To weigh the …

Insights from one thousand cloned dogs

PO Olsson, YW Jeong, Y Jeong, M Kang, GB Park… - Scientific Reports, 2022 - nature.com
Animal cloning has been popularized for more than two decades, since the birth of Dolly the
Sheep 25 years ago in 1996. There has been an apparent waning of interest in cloning …

Interspecies somatic cell nuclear transfer: advancements and problems

I Lagutina, H Fulka, G Lazzari, C Galli - … (Formerly" Cloning and …, 2013 - liebertpub.com
Embryologists working with livestock species were the pioneers in the field of
reprogramming by somatic cell nuclear transfer (SCNT). Without the “Dolly experiment,” the …