Reactive oxygen species (ROS) and mitochondria play a pivotal role in regulating platelet
functions. Platelet activation determines a drastic change in redox balance and in platelet …

Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, is considered
one of the most common causes of dementia worldwide, accounting for about 80% of all …

It is now apparent that platelet function is more diverse than originally thought, shifting the
view of platelets from blood cells involved in hemostasis and wound healing to major …

Cardiovascular disease (CVD), such as hypertension and atherosclerosis, is the leading
cause of global death. Endothelial dysfunction (ED) is a strong predictor for most CVD …

Aims: Redox signaling plays a key role in skeletal muscle remodeling induced by exercise
and prolonged inactivity, but it is unclear which oxidant triggers myofiber hypertrophy due to …

Placozoa is a phylum of non-bilaterian marine animals. These small, flat organisms adhere
to the substrate via their densely ciliated ventral epithelium, which mediates mucociliary …

Under dysbiosis, a gut metabolic disorder, short-chain carboxylic acids (SCCAs) are
secreted to the lumen, affecting colorectal cancer (CRC) development. Butyrate and …

The progression of Alzheimer's dementia is associated with neurovasculature impairment,
which includes inflammation, microthromboses, and reduced cerebral blood flow. Here, we …

NADPH oxidase (NOX) enzymes are involved in a various physiological and pathological
processes such as platelet activation and inflammation. Interestingly, we found that the pan …

The regulation of platelets by oxidants is critical for vascular health and may explain
thrombotic complications in diseases such as diabetes and dementia, but remains poorly …