Integrated therapy for HIV and tuberculosis
W Manosuthi, S Wiboonchutikul… - AIDS research and …, 2016 - Springer
Tuberculosis (TB) has been the most common opportunistic infection and cause of mortality
among HIV-infected patients, especially in resource-limited countries. Clinical …
among HIV-infected patients, especially in resource-limited countries. Clinical …
Safety implications of combined antiretroviral and anti-tuberculosis drugs
M Cerrone, M Bracchi, S Wasserman… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Antiretroviral and anti-tuberculosis (TB) drugs are often co-administered in
people living with HIV (PLWH). Early initiation of antiretroviral therapy (ART) during TB …
people living with HIV (PLWH). Early initiation of antiretroviral therapy (ART) during TB …
Detection of tuberculosis recurrence, diagnosis and treatment response by a blood transcriptomic risk signature in HIV-infected persons on antiretroviral therapy
HIV-infected individuals are at high risk of tuberculosis disease and those with prior
tuberculosis episodes are at even higher risk of disease recurrence. A non-sputum …
tuberculosis episodes are at even higher risk of disease recurrence. A non-sputum …
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a …
JK Mukonzo, A Okwera, N Nakasujja, H Luzze… - BMC infectious …, 2013 - Springer
Background HIV infection, anti-tuberculosis and efavirenz therapy are associated with
neuropsychological effects. We evaluated the influence of rifampicin cotreatment, efavirenz …
neuropsychological effects. We evaluated the influence of rifampicin cotreatment, efavirenz …
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: a randomised non-inferiority trial
M Bonnet, N Bhatt, E Baudin, C Silva… - The Lancet infectious …, 2013 - thelancet.com
Background In countries with a high incidence of HIV and tuberculosis co-infection,
nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with …
nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with …
Efavirenz a nonnucleoside reverse transcriptase inhibitor of first-generation: Approaches based on its medicinal chemistry
Acquired immunodeficiency syndrome (AIDS) is a disease caused by human
immunodeficiency virus (HIV) that affects individuals on all continents. In 1987, the …
immunodeficiency virus (HIV) that affects individuals on all continents. In 1987, the …
Pharmacological interactions between rifampicin and antiretroviral drugs: challenges and research priorities for resource-limited settings
HH Semvua, GS Kibiki, ER Kisanga… - Therapeutic drug …, 2015 - journals.lww.com
Coadministration of antituberculosis and antiretroviral therapy is often inevitable in high-
burden countries where tuberculosis (TB) is the most common opportunistic infection …
burden countries where tuberculosis (TB) is the most common opportunistic infection …
Relationship between weight, efavirenz exposure, and virologic suppression in HIV-infected patients on rifampin-based tuberculosis treatment in the AIDS Clinical …
AF Luetkemeyer, SL Rosenkranz, D Lu… - Clinical infectious …, 2013 - academic.oup.com
Abstract Background. Rifampin (RIF) upregulates CYP 450 isoenzymes, potentially lowering
efavirenz (EFV) exposure. The US EFV package insert recommends an EFV dose increase …
efavirenz (EFV) exposure. The US EFV package insert recommends an EFV dose increase …
When to start antiretroviral therapy during tuberculosis treatment?
The trial data support the World Health Organization recommendations on when to start ART
in TB–HIV coinfected patients including earlier ART initiation in severely immune …
in TB–HIV coinfected patients including earlier ART initiation in severely immune …
Effects of rifampin-based antituberculosis therapy on plasma efavirenz concentrations in children vary by CYP2B6 genotype
Objectives: An efavirenz-based antiretroviral therapy (ART) regimen is preferred for children
more than 3 years of age with tuberculosis. However, rifampin, a key component of …
more than 3 years of age with tuberculosis. However, rifampin, a key component of …