Friedelin and 3β-friedelinol: pharmacological activities

MH Radi, RA El-Shiekh, AM El-Halawany… - Revista Brasileira de …, 2023 - Springer
The interest in herbal medicine as a source of drug leads is being reinforced, especially for
tackling challenging therapeutic areas such as antimicrobial resistance, cardiovascular …

Evaluating Cannabis sativa L.'s neuroprotection potential: From bench to bedside

JS Laws III, SD Smid - Phytomedicine, 2022 - Elsevier
Background Neurodegenerative diseases and dementia pose a global health challenge in
an aging population, exemplified by the increasing incidence and prevalence of its most …

[HTML][HTML] Ranuncoside's attenuation of scopolamine-induced memory impairment in mice via Nrf2 and NF-ĸB signaling

HS Salahuddin, S Attaullah, SA Shah, SU Khan… - Saudi Pharmaceutical …, 2023 - Elsevier
Scopolamine is a well-known pharmacological agent responsible for causing memory
impairment in animals, as well as oxidative stress and neuroinflammation inducer which …

[HTML][HTML] Vitamin B1 via Nrf-2/TLR4 signaling pathway ameliorates scopolamine-induced memory dysfunction in adult mice

A Nasir, M Khan, S Noreen, MU Rahman… - Arabian Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
memory impairment and cognitive decline, with oxidative stress and neuroinflammation …

Natural flavonoids as potential therapeutics in the management of Alzheimer's disease: a review

PT Nguyen-Thi, TK Vo, THT Pham, TT Nguyen… - 3 Biotech, 2024 - Springer
Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder which is
associated with the accumulation of proteotoxic Aβ peptides, and pathologically …

Current Perspectives: Obesity and Neurodegeneration-Links and Risks

PJ Kueck, JK Morris, JA Stanford - Degenerative neurological and …, 2024 - Taylor & Francis
Obesity is increasing in prevalence across all age groups. Long-term obesity can lead to the
development of metabolic and cardiovascular diseases through its effects on adipose …

Analysis of 14 terpenoids and sterols and variety discrimination of Codonopsis Radix using ultra‐high‐performance liquid chromatography‐quadrupole‐time‐of‐flight …

W Li, X Xu, Z Tang, Y Guo, D Fei… - Journal of Separation …, 2023 - Wiley Online Library
Recently, we confirmed that the 95% ethanol‐extracted fraction of Codonopsis Radix, which
contains several triterpenoids and sterols, possesses pharmacological activities. However …

Montelukast Ameliorates Scopolamine-induced Alzheimer's Disease: Role on Cholinergic Neurotransmission, Antioxidant Defence System, Neuroinflammation and …

B Yerraguravagari, NP Penchikala… - CNS & Neurological …, 2024 - ingentaconnect.com
Background: Alzheimer's disease (AD) is an overwhelming neurodegenerative disease with
progressive loss of memory. AD is characterized by the deposition of the senile plaques …

Optimizing extraction conditions and isolation of bound phenolic compounds from corn silk (Stigma maydis) and their antioxidant effects

U Khan, F Hayat, F Khanum, Y Shao… - Journal of Food …, 2023 - Wiley Online Library
During the processing of maize, Stigma maydis, also known as corn silk, is normally
discarded as waste. Phytochemical research was carried out on the S. maydis to use it as a …

Genetic deletion of astrocytic calcineurin B1 prevents cognitive impairment and neuropathology development in acute and chronic mouse models of Alzheimer's …

L Tapella, G Dematteis, P La Vitola, S Leva, E Tonelli… - Glia, 2024 - Wiley Online Library
Alzheimer's disease (AD) represents an urgent yet unmet challenge for modern society,
calling for exploration of innovative targets and therapeutic approaches. Astrocytes, main …