Brain perivascular macrophages are specialized populations of macrophages that reside in
the space around cerebral vessels, such as penetrating arteries and venules. With the help …

Pathological angiogenesis is a major cause of irreversible blindness in individuals of all age
groups with proliferative retinopathy (PR). Mononuclear phagocytes (MPs) within …

The relationships between tissue-resident microglia and early macrophages, especially their
lineage segregation outside the yolk sac, have been recently explored, providing a model in …

Microglia are the resident immune cells of the central nervous system (CNS). Microglia
originate from erythromyeloid progenitors in the yolk sac at the early embryonic stage, and …

The overproduction of cells and subsequent production of debris is a universal principle of
neurodevelopment. Here, we show an additional feature of the developing nervous system …

Oxidative stress is a crucial mechanism in the pathophysiology of lung injury/fibrosis and
diaphragmatic dysfunction. Yes-associated protein 1 (YAP1) is a key oxidative stress …

Microglia, the crucial immune cells inhabiting the central nervous system (CNS), perform a
range of vital functions, encompassing immune defense and neuronal regulation. Microglia …

Myelin is the membrane surrounding neuronal axons in the central nervous system (CNS),
produced by oligodendrocytes to provide insulation for electrical impulse conduction and …

The mononuclear phagocyte system (MPS) was defined in the early 1970s as a family of
cells including progenitors, monocytes in the circulation, and resident tissue macrophages …

Meningeal lymphatic vessels form a relationship between the nervous system and
periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not …