Purpose A pathologic complete response (pCR; ypT0N0) of a rectal tumor after neoadjuvant
radiochemotherapy (RCT) is associated with an excellent prognosis. Several retrospective …

Context.—Pathologic assessment of colorectal cancer resection specimens plays an
important role in postsurgical management and prognostication in patients with colorectal …

Neoadjuvant therapy is increasingly used to treat patients with a wide variety of
malignancies. Histologic evaluation of treated specimens provides important prognostic …

Challenges exist with standardized colorectal cancer reporting despite adoption of the
American Joint Committee on Cancer-Staging Manual 8th edition. We performed this study …

Mismatch-repair deficiency in solid tumors predicts their response to PD-1 blockade. Based
on this principle, pembrolizumab is approved as standard of care for patients with …

Abstract Background Epstein–Barr virus positivity (EBV+) and microsatellite instability (MSI-
high) are positive prognostic factors for survival in resectable gastric cancer (GC). However …

In around 30% of patients, non-small cell lung cancer is diagnosed at an advanced but
resectable stage. Adding systemic therapy has shown clear benefit over surgery alone in …

AIM To clarify which factors may influence pathological tumor response and affect clinical
outcomes in patients with locally advanced rectal carcinoma treated with neo-adjuvant …

Aim To evaluate the pattern of tumor relapse of pathological complete response (pCR)
patients with locally advanced rectal cancer (LARC) following neoadjuvant …

Background: Approximately 15–30% of locally advanced rectal cancer (LARC) patients
achieved pathological complete response (pCR) after neoadjuvant chemoradiotherapy …