Barrier epithelial cells and the control of type 2 immunity

H Hammad, BN Lambrecht - Immunity, 2015 - cell.com
Type-2-cell-mediated immunity, rich in eosinophils, basophils, mast cells, CD4+ T helper 2
(Th2) cells, and type 2 innate lymphoid cells (ILC2s), protects the host from helminth …

Macrophage polarization in response to epigenetic modifiers during infection and inflammation

U Patel, S Rajasingh, S Samanta, T Cao, B Dawn… - Drug discovery today, 2017 - Elsevier
Highlights•This review is focusing on polarization of macrophages by epigenetic
modifications.•M1/M2 macrophages are flawlessly synchronized, specialized, and perform …

[HTML][HTML] Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather …

S He, Q Yu, Y He, R Hu, S Xia, J He - Poultry Science, 2019 - Elsevier
The aim of this study was to investigate the effect of dietary resveratrol supplementation on
innate immunity and inflammatory responses in the spleen of yellow-feather broilers under …

Expanding the applications of microneedles in dermatology

AH Sabri, J Ogilvie, K Abdulhamid, V Shpadaruk… - European Journal of …, 2019 - Elsevier
Since the first patent for microneedles was filed in the 1970s, research on utilising
microneedles as a drug delivery system has progressed significantly. In addition to the …

Molecular targets of quercetin with anti-inflammatory properties in atopic dermatitis

V Karuppagounder, S Arumugam… - Drug discovery today, 2016 - Elsevier
Highlights•Atopic dermatitis (AD) is a chronic inflammatory skin disease.•Multiple signaling
pathways may combine to produce pathological changes in AD.•Quercetin is a potent …

Hyaluronic acid hydrogel containing resveratrol-loaded chitosan nanoparticles as an adjuvant in atopic dermatitis treatment

R Conte, I De Luca, A Valentino, P Cerruti… - Journal of Functional …, 2023 - mdpi.com
Atopic dermatitis (AD) is a common disease-causing skin inflammation, redness, and
irritation, which can eventually result in infection that drastically impacts patient quality of life …

Resveratrol and its derivatives in inflammatory skin disorders—Atopic dermatitis and psoriasis: A review

M Marko, R Pawliczak - Antioxidants, 2023 - mdpi.com
Atopic dermatitis (AD) and psoriasis are inflammatory skin diseases whose prevalence has
increased worldwide in recent decades. These disorders contribute to patients' decreased …

Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes

J Focken, J Scheurer, A Jäger, CM Schürch… - Cell Reports, 2023 - cell.com
Staphylococcus aureus is the most common cause of bacterial skin infections in humans,
including patients with atopic dermatitis (AD). Polymorphonuclear neutrophils (PMNs) are …

Modulation of HMGB1 translocation and RAGE/NFκB cascade by quercetin treatment mitigates atopic dermatitis in NC/Nga transgenic mice

V Karuppagounder, S Arumugam… - Experimental …, 2015 - Wiley Online Library
Quercetin, glycosylated form of flavonoid compound, has potent antioxidant and anti‐
inflammatory properties. In this study, we have investigated the effects of quercetin on skin …

Signal transduction pathways activated by innate immunity in mast cells: translating sensing of changes into specific responses

ZP Espinosa-Riquer, D Segura-Villalobos… - Cells, 2020 - mdpi.com
Mast cells (MCs) constitute an essential cell lineage that participates in innate and adaptive
immune responses and whose phenotype and function are influenced by tissue-specific …