Hepatic lipid metabolism is a series of complex processes that control influx and efflux of not
only hepatic lipid pools, but also organismal pools. Lipid homeostasis is usually tightly …

Obesity is characterized by increased storage of fatty acids in an expanded adipose tissue
mass and is closely associated with the development of insulin resistance in peripheral …

Over the past decade and a half it has become increasingly clear that adipose tissue is a
much more complex organ than was initially considered and that its metabolic functions …

Although there are numerous experimental data indicating that oxidative stress plays a role
in the initiation and progression of alcohol-induced liver disease (ALD), this work has yet to …

A combination of insulin resistance and pancreatic β‐cell dysfunction underlies most cases
of type 2 diabetes. While the interplay of these two impairments is believed to be important in …

Alcoholic liver disease (ALD) remains a major cause of morbidity and mortality worldwide.
For example, the Veterans Administration Cooperative Studies reported that patients with …

Alcoholic fatty liver disease (AFLD), a potentially pathologic condition, can progress to
steatohepatitis, fibrosis, and cirrhosis, leading to an increased probability of hepatic failure …

Alcoholic liver disease (ALD) and hepatitis C virus (HCV) infection represent, either alone or
in combination, more than two thirds of all patients with liver disease in the Western world …

Alcohol consumption is customary in most cultures and alcohol abuse is common
worldwide. For example, more than 50% of Americans consume alcohol, with an estimated …

Alcoholic liver disease (ALD) remains a major cause of morbidity and mortality worldwide.
For example, the Veterans Administration Cooperative Studies reported that patients with …