Several epidemiological observations have shown an inverse relation between
consumption of plant-based foods, rich in phytochemicals, and incidence of cancer …

Aurora kinases, a family of serine/threonine kinases, consisting of Aurora A (AURKA),
Aurora B (AURKB) and Aurora C (AURKC), are essential kinases for cell division via …

Phosphoproteomics and proteomics experiments capture a global snapshot of the cellular
signaling network, but these methods do not directly measure kinase state. Kinase …

Aurora kinase B (AURKB) is a mitotic serine/threonine protein kinase that belongs to the
aurora kinase family along with aurora kinase A (AURKA) and aurora kinase C (AURKC) …

We have developed a deep-scale proteome and phosphoproteome database from 44
representative acute myeloid leukemia (AML) patients from the LAML TCGA dataset and 6 …

Post-translational modifications such as ubiquitination play important regulatory roles in
several biological processes in eukaryotes. This process could be reversed by …

Probiotic roles of Clostridium butyricum (CB) are involved in regulating disease and cancers,
yet the mechanistic basis for these regulatory roles remains largely unknown. Here, we …

Motivation Combining P-values from multiple statistical tests is a common exercise in
bioinformatics. However, this procedure is non-trivial for dependent P-values. Here, we …

The cellular phenotype is described by a complex network of molecular interactions.
Elucidating network properties that distinguish disease from the healthy cellular state is …

Aurora kinase B, one of the three members of the mammalian Aurora kinase family, is the
catalytic component of the chromosomal passenger complex, an essential regulator of …