Ligand-based active targeting strategies for cancer theranostics

A Bandyopadhyay, T Das, S Nandy, S Sahib… - Naunyn-Schmiedeberg's …, 2023 - Springer
In the past decades, for the intermediate or advanced cancerous stages, preclinical and
clinical applications of nanomedicines in cancer theranostics have been extensively studied …

Do bacteria provide an alternative to cancer treatment and what role does lactic acid bacteria play?

LMT Dicks, W Vermeulen - Microorganisms, 2022 - mdpi.com
Cancer is one of the leading causes of mortality and morbidity worldwide. According to 2022
statistics from the World Health Organization (WHO), close to 10 million deaths have been …

Combination Nano-Delivery Systems Remodel the Immunosuppressive Tumor Microenvironment for Metastatic Triple-Negative Breast Cancer Therapy

L Bai, H Liu, R You, X Jiang, T Zhang, Y Li… - Molecular …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer for which
effective therapies are lacking. Targeted remodeling of the immunosuppressive tumor …

Effective blocking of neuropilin-1activity using oligoclonal nanobodies targeting different epitopes

E Karami, M Mesbahi Moghaddam… - Preparative …, 2023 - Taylor & Francis
Abstract Neuropilin-1 (NRP-1) is a non-tyrosine kinase receptor and when overexpressed,
leads to angiogenesis. High expression of NRP-1 has been observed in various cancers …

[PDF][PDF] Interactions Between Gut Microbiota and the Central Nervous System, with Emphasis on Quorum Sensing Between Commensal Lactic Acid Bacteria and …

LMT Dicks - 2023 - scholar.sun.ac.za
The human gut hosts close to 4 trillion microorganisms, which is nearly equivalent to the
estimated 3.0× 1013 human cells in a 70 kg body. Although the composition of gut …

Comparison of Five Escherichia coli Strains to Achieve the Maximum Yield of a Recombinant Immunotoxin Consisting of an Antibody against VEGF Conjugated with …

M Zarei, MH Morowvat - Recent Patents on Biotechnology, 2024 - ingentaconnect.com
Background: Cancer is among the leading causes of death worldwide, imposing high costs
on the health systems of all societies. Extensive biological studies are required to discover …

In Vitro and In Vivo Studies of a Heminecrolysin Toxin–VEGF Fusion Protein as a Novel Therapeutic for Solid Tumor Targeting

Z Naderiyan, N Sotoudeh, A Shoari, H Ghaderi… - Molecular …, 2023 - Springer
Angiogenesis, the formation of new vessels, is a critical step in the malignancy progression
of solid tumors. Many investigations have demonstrated the usefulness of immunotoxins to …