Simple Summary Vimentin is an important filamentous protein providing structural and
functional support to the cell. During initial stages of cancer development, vimentin …

Our traditional understanding of phenotypic plasticity in adult somatic cells comprises
dedifferentiation and transdifferentiation in the context of tissue regeneration or wound …

Over the last decade, important clinical benefits have been achieved in cancer patients by
using drug-targeting strategies. Nevertheless, drug resistance is still a major problem in …

The plasticity of cancer cells underlies their capacity to adapt to the selective pressures they
encounter during tumour development. Aberrant reactivation of epithelial–mesenchymal …

Tumor metastasis is a multistep process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. Metastasis occurs through a series of steps …

Epithelial-mesenchymal transition (EMT) is a highly conserved process in which polarized,
immobile epithelial cells lose tight junctions, associated adherence, and become migratory …

Reactivation of an embryonic epithelial-to-mesenchymal (EMT) program is commonly
accepted as a core component of carcinoma progression. Collectively, EMT and …

Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome,,
yet their potential involvement in human disease is not well understood,. Recent studies of …

The embryonic programme 'epithelial–mesenchymal transition'(EMT) is thought to promote
malignant tumour progression. The transcriptional repressor zinc‐finger E‐box binding …

Malignant progression in cancer requires populations of tumor-initiating cells (TICs)
endowed with unlimited self renewal, survival under stress, and establishment of distant …