Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …

Interest in neurofilaments has risen sharply in recent years with recognition of their potential
as biomarkers of brain injury or neurodegeneration in CSF and blood. This is in the context …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two related
currently incurable neurodegenerative diseases. ALS is characterized by degeneration of …

Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

Neuronal endosomal dysfunction, the earliest known pathobiology specific to Alzheimer's
disease (AD), is mediated by the aberrant activation of Rab5 triggered by APP-β secretase …

How macroautophagy/autophagy influences neurofilament (NF) proteins in neurons, a
frequent target in neurodegenerative diseases and injury, is not known. NFs in axons have …

In the last two years, neurofilaments (NFs) have become one of the most blazing topics in
clinical neuroscience. NFs are major cytoskeletal constituents of neurons, can be detected in …

The recent introduction of new-generation immunoassay methods allows the reliable
quantification of structural brain markers in peripheral matrices. Neurofilament light chain …

Neurofilament light (NFL) is one of the proteins forming multimeric neuron-specific
intermediate filaments, neurofilaments, which fill the axonal cytoplasm, establish caliber …

As per the latest ILAE definition, status epilepticus (SE) may lead to long-term irreversible
consequences, such as neuronal death, neuronal injury, and alterations in neuronal …