The role of myofibroblasts in physiological and pathological tissue repair
Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …
Neutrophils in tissue trauma of the skin, bone, and lung: two sides of the same coin
A Kovtun, DAC Messerer… - Journal of …, 2018 - Wiley Online Library
Following severe tissue injury, patients are exposed to various danger‐and microbe‐
associated molecular patterns, which provoke a strong activation of the neutrophil defense …
associated molecular patterns, which provoke a strong activation of the neutrophil defense …
Scarless wound healing: from development to senescence
An essential element of tissue homeostasis is the response to injuries, cutaneous wound
healing being the most studied example. In the adults, wound healing aims at quickly …
healing being the most studied example. In the adults, wound healing aims at quickly …
Anti-fibrotic effects of statin drugs: A review of evidence and mechanisms
Fibrosis is a pathological repair process common among organs, that responds to tissue
damage by replacement with non-functional connective tissue. Despite the widespread …
damage by replacement with non-functional connective tissue. Despite the widespread …
Therapeutic strategies to reduce burn wound conversion
A Palackic, JW Jay, RP Duggan, LK Branski, SE Wolf… - Medicina, 2022 - mdpi.com
Burn wound conversion refers to the phenomenon whereby superficial burns that appear to
retain the ability to spontaneously heal, convert later into deeper wounds in need of …
retain the ability to spontaneously heal, convert later into deeper wounds in need of …
Advances in immunomodulation and immune engineering approaches to improve healing of extremity wounds
PJ Muire, MA Thompson, RJ Christy… - International Journal of …, 2022 - mdpi.com
Delayed healing of traumatic wounds often stems from a dysregulated immune response
initiated or exacerbated by existing comorbidities, multiple tissue injury or wound …
initiated or exacerbated by existing comorbidities, multiple tissue injury or wound …
Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing
Here, an oxidation/acid dual-responsive nanohybrids/ark system was produced. The
microfluidics-produced nanohybrids endow the system with an orchestrated cascade from …
microfluidics-produced nanohybrids endow the system with an orchestrated cascade from …
The role of the inflammatory response in burn injury
XL Strudwick, AJ Cowin - Hot topics in burn injuries. Adelaide …, 2018 - books.google.com
Burns are characterised by significant local swelling and redness around the site of injury,
indicative of acute inflammation. Whilst the inflammatory response is fundamental to the …
indicative of acute inflammation. Whilst the inflammatory response is fundamental to the …
Pharmacotherapy for keloids and hypertrophic scars
T Murakami, S Shigeki - International Journal of Molecular Sciences, 2024 - mdpi.com
Keloids (KD) and hypertrophic scars (HTS), which are quite raised and pigmented and have
increased vascularization and cellularity, are formed due to the impaired healing process of …
increased vascularization and cellularity, are formed due to the impaired healing process of …
Balance and circumstance: the renin angiotensin system in wound healing and fibrosis
R Bernasconi, A Nyström - Cellular signalling, 2018 - Elsevier
The tissue renin angiotensin system (tRAS) is a locally-acting master-modulator of tissue
homeostasis and regeneration. Through these abilities, it is emerging as an attractive target …
homeostasis and regeneration. Through these abilities, it is emerging as an attractive target …