Alternative Reactions to Friedel-crafts Acylation on Highly Activated Substrates
DI Leite, LCF Pimentel, MC Avelino Dias… - Current Organic …, 2024 - ingentaconnect.com
Friedel-crafts acylation (FCAcyl) is the most widespread method used to prepare aryl
ketones and aldehydes. However, depending on the type of group attached to the benzene …
ketones and aldehydes. However, depending on the type of group attached to the benzene …
DBU-catalyzed dearomative annulation of 2-pyridylacetates with α, β-unsaturated pyrazolamides for the synthesis of multisubstituted 2, 3-dihydro-4 H-quinolizin-4 …
YB Shen, JQ Zhao, ZH Wang, Y You… - Organic Chemistry …, 2022 - pubs.rsc.org
The reaction of 2-pyridylacetates and α, β-unsaturated pyrazolamides with DBU as the
catalyst has been developed. A range of unexplored multisubstituted 2, 3-dihydro-4H …
catalyst has been developed. A range of unexplored multisubstituted 2, 3-dihydro-4H …
Integrated structure-guided computational design of novel substituted quinolizin-4-ones as Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) …
Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) is a known drug target
for the development of antimalarial agents. Herein, we presented integrated structure …
for the development of antimalarial agents. Herein, we presented integrated structure …
Simple pyrazoles as efficient organocatalysts for alkyne–CO 2 carboxylation and one-pot construction of heterocycles
L Zhang, G Li, EH Xing, Y Liu, C Jin, Z Du… - Organic Chemistry …, 2024 - pubs.rsc.org
C–H carboxylation of alkynes with CO2 is a straightforward and atom-economical approach
toward propiolic acids. Transition metal catalysis for this reaction has been intensively …
toward propiolic acids. Transition metal catalysis for this reaction has been intensively …
The literature of heterocyclic chemistry, Part XX, 2020
LI Belen'kii, GA Gazieva, YB Evdokimenkova… - Advances in …, 2023 - Elsevier
A systematized survey of reviews and monographs published in 2020 on all aspects of
heterocyclic chemistry is given. Methods for the synthesis, reactivity, and practically useful …
heterocyclic chemistry is given. Methods for the synthesis, reactivity, and practically useful …