Stem cells and regenerative medicine: myth or reality of the 21th century

JF Stoltz, N de Isla, YP Li, D Bensoussan… - Stem cells …, 2015 - Wiley Online Library
Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

Glutathione compartmentalization and its role in glutathionylation and other regulatory processes of cellular pathways

A Scirè, L Cianfruglia, C Minnelli, D Bartolini… - Biofactors, 2019 - Wiley Online Library
Glutathione is considered the major non‐protein low molecular weight modulator of redox
processes and the most important thiol reducing agent of the cell. The biosynthesis of …

Regulation of the mitochondrial reactive oxygen species: Strategies to control mesenchymal stem cell fates ex vivo and in vivo

C Hu, L Zhao, C Peng, L Li - Journal of cellular and molecular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSC s) are broadly used in cell‐based regenerative medicine
because of their self‐renewal and multilineage potencies in vitro and in vivo. To ensure …

Antioxidant and reactive oxygen species scavenging properties of cellular albumin in HepG2 cells is mediated by the glutathione redox system

A Seidkhani‐Nahal, A Allameh… - Biotechnology and …, 2019 - Wiley Online Library
This study was carried out to examine the role of intracellular albumin in the modulation of
oxidative damage induced by glutathione modifiers in HepG2 cells. Also, the relationship of …

From gametogenesis and stem cells to cancer: common metabolic themes

SL Pereira, AS Rodrigues, MI Sousa… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND Both pluripotent stem cells (PSCs) and cancer cells have been described
as having similar metabolic pathways, most notably a penchant for favoring glycolysis even …

The role of albumin and PPAR‐α in differentiation‐dependent change of fatty acid profile during differentiation of mesenchymal stem cells to hepatocyte‐like cells

S Esmaeli, A Allameh, M Soleimani… - Cell biochemistry …, 2014 - Wiley Online Library
Differentiation of mesenchymal stem cells (MSCs) to hepatocyte‐like cells is associated with
morphological and biological changes. In this study, the effect of hepatogenic differentiation …

[HTML][HTML] Glutathione-related inflammatory signature in hepatocytes differentiated from the progenitor mesenchymal stem cells

A Allameh, HR Ahmadi-Ashtiani, N Maleki - Heliyon, 2020 - cell.com
N-acetylcysteine (NAC) as a glutathione inducer is known for its anti-inflammatory effects in
inflammatory conditions. The aim of the present study was to know if supplementation of the …

Healing potential of stem cells for diabetic ulcers

H Ahmadi Ashtiani, A Firooz, H Rastegar… - … of Dermatology and …, 2020 - jdc.tums.ac.ir
A wound is described as any laceration in normal anatomic structure and functional integrity
of the skin. Chronic wounds don't progress through the normal wound healing process in 3 …

Differences in growth response of human hair follicle mesenchymal stem cells to herbal extracts and a growth factor

HR Ahmadi Ashtiani, F Salehinia, H Rastegar… - Journal of Medicinal …, 2018 - jmp.ir
Background: One of the key questions in biochemistry is why cell becomes aged and what
are the involved factors? Why cell growth is stopped after some divisions and cells become …

Role of glutathione in balancing total antioxidant status and generation of reactive oxygen species during hepatic differentiation of bone-marrow-derived …

A Allameh, HR Ahmadi-Ashtiani… - Journal of Stem …, 2018 - search.proquest.com
Differentiation of mesenchyal stem cells (MSCs) into biologically active hepatocytes
depends on several factors. Glutathione (GSH) and antioxidant enzymes play major role in …